CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

Abroad (travel likely)RecruitingPHASE2

Conditions

Advanced Biliary Tract Carcinoma · Advanced Colorectal Carcinoma · Advanced Gastroesophageal Junction Adenocarcinoma · Advanced Lung Adenocarcinoma · Advanced Malignant Solid Neoplasm · Advanced Ovarian Carcinoma · Advanced Pancreatic Carcinoma · Advanced Urothelial Carcinoma · Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 · Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 · Metastatic Biliary Tract Carcinoma · Metastatic Colorectal Carcinoma · Metastatic Gastroesophageal Junction Adenocarcinoma · Metastatic Lung Adenocarcinoma · Metastatic Ovarian Carcinoma · Metastatic Pancreatic Carcinoma · Metastatic Urothelial Carcinoma · Refractory Biliary Tract Carcinoma · Refractory Colorectal Carcinoma · Refractory Gastroesophageal Junction Adenocarcinoma · Refractory Lung Adenocarcinoma · Refractory Ovarian Carcinoma · Refractory Pancreatic Carcinoma · Refractory Urothelial Carcinoma · Stage II Pancreatic Cancer AJCC v8 · Stage III Colorectal Cancer AJCC v8 · Stage III Lung Cancer AJCC v8 · Stage III Ovarian Cancer AJCC v8 · Stage III Pancreatic Cancer AJCC v8 · Stage IV Colorectal Cancer AJCC v8 · Stage IV Lung Cancer AJCC v8 · Stage IV Ovarian Cancer AJCC v8 · Stage IV Pancreatic Cancer AJCC v8

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Locations

Northwestern University, Chicago, Illinois, United States
Contact: Study coordinator (Devalingam Mahalingam, MD, PhD) · mahalingam@nm.org · 312-695-6929
Contact: Principal Investigator (Devalingam Mahalingam, MD, PhD)

Study leads

Devalingam Mahalingam
Principal Investigator
Northwestern University

View source on ClinicalTrials.gov

Similar trials

Other trials that are currently recruiting and may be relevant based on condition, treatment, phase, or location

XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies.

Pancreatic Adenocarcinoma Metastatic · Lung Cancer (NSCLC) · Ovarian Cancer

Abroad (travel likely)RecruitingPHASE1, PHASE2

Jinan, China

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Advanced Solid Tumor · Advanced Malignant Neoplasm · Metastatic Cancer

Abroad (travel likely)RecruitingPHASE1, PHASE2

Irvine, United States · La Jolla, United States

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

Biliary Tract Cancer · Breast Cancer · Cervical Cancer

Abroad (travel likely)RecruitingPHASE1, PHASE2

Denver, United States · Miami, United States

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

Head and Neck Squamous Cell Carcinoma (HNSCC) · Non-small Cell Lung Cancer (NSCLC) · Esophageal Cancer

Abroad (travel likely)RecruitingPHASE1, PHASE2

Los Angeles, United States · Grand Rapids, United States