Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

IsraelRecruitingPHASE2, PHASE3

Conditions

Urothelial Cancer

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Locations

Local Institution - 0167, Gilbert, Arizona, United States
Local Institution - 0162, Fullerton, California, United States
Local Institution - 0252, Palo Alto, California, United States
Local Institution - 0163, Sacramento, California, United States
University of California Davis (UC Davis) Comprehensive Cancer Center, Sacramento, California, United States
Local Institution - 0251, San Francisco, California, United States
Local Institution - 0254, Santa Rosa, California, United States
Local Institution - 0245, Dillon, Colorado, United States
Shaw Cancer Center, Edwards, Colorado, United States
Sibley Memorial Hospital, Washington D.C., District of Columbia, United States
Local Institution - 0247, Miami, Florida, United States
University of Kentucky Chandler Medical Center, Lexington, Kentucky, United States
Johns Hopkins Hospital, Baltimore, Maryland, United States
Local Institution - 0195, Boston, Massachusetts, United States
Karmanos Cancer Institute, Detroit, Michigan, United States
Local Institution - 0248, Buffalo, New York, United States
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Fairview Hospital, Cleveland, Ohio, United States
Cleveland Clinic, Cleveland, Ohio, United States
Local Institution - 0161, Columbus, Ohio, United States
Cleveland Clinic - Hillcrest Hospital, Mayfield Heights, Ohio, United States
Local Institution - 0141, Portland, Oregon, United States
Local Institution - 0186, Nashville, Tennessee, United States
Local Institution - 0084, Nashville, Tennessee, United States
Local Institution - 0249, Abilene, Texas, United States
Local Institution - 0187, Austin, Texas, United States
Intermountain Medical Center, Murray, Utah, United States
Local Institution - 0253, St. George, Utah, United States
University of Virginia Health System, Charlottesville, Virginia, United States
Local Institution - 0188, Norfolk, Virginia, United States
Local Institution - 0200, Seattle, Washington, United States
Local Institution - 0255, Seattle, Washington, United States
Local Institution - 0028, CABA, Buenos Aires, Argentina
Local Institution - 0023, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
Local Institution - 0024, ABB, Buenos Aires F.D., Argentina
Local Institution - 0026, Buenos Aires, Buenos Aires F.D., Argentina
Local Institution - 0025, Córdoba, Argentina
Local Institution - 0027, Mendoza, Argentina
Macquarie University, Macquarie University, New South Wales, Australia
GenesisCare North Shore, St Leonards, New South Wales, Australia
Austin Health, Heidelberg, Victoria, Australia
Medizinische Universität Wien, Vienna, State of Vienna, Austria
Klinik Ottakring, Vienna, State of Vienna, Austria
Medizinische Universitaet Innsbruck, Innsbruck, Tyrol, Austria
ZAS Augustinus, Wilrijk, Antwerpen, Belgium
AZ Maria Middelares, Ghent, Oost-Vlaanderen, Belgium
UZ Gent, Ghent, Oost-Vlaanderen, Belgium
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman, Liège, Belgium
Local Institution - 0129, Salvador, Estado de Bahia, Brazil
Local Institution - 0121, Porto Alegre, Rio Grande do Sul, Brazil
Local Institution - 0130, Rio de Janeiro, Brazil
Local Institution - 0124, São Paulo, Brazil
Local Institution - 0020, Edmonton, Alberta, Canada
The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada
Princess Margaret Cancer Centre, Toronto, Ontario, Canada
McGill University Health Centre, Montreal, Quebec, Canada
Local Institution - 0050, Beijing, Beijing Municipality, China
Local Institution - 0224, Beijing, Beijing Municipality, China
Local Institution - 0048, Fuzhou, Fujian, China
The First Affiliated Hospital Of Fujian Medical University, Fuzhou, Fujian, China
Local Institution - 0056, Xiamen, Fujian, China
Local Institution - 0051, Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
Zhujiang Hospital, Guangzhou, Guangdong, China
Local Institution - 0201, Wuhan, Hubei, China
Local Institution - 0059, Changsha, Hunan, China
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China
Local Institution - 0046, Nanjing, Jiangsu, China
Local Institution - 0114, Nantong, Jiangsu, China
Local Institution - 0206, Nanchang, Jiangxi, China
Shandong Cancer Hospital, Jinan, Shandong, China
Local Institution - 0156, Qingdao, Shandong, China
Yantai Yuhuangding Hospital, Yantai, Shandong, China
Local Institution - 0042, Shanghai, Shanghai Municipality, China
West China Hospital, Sichuan University, Chengdu, Sichuan, China
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin Municipality, China
Local Institution - 0227, Tianjin, Tianjin Municipality, China
Local Institution - 0157, Hangzhou, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Local Institution - 0064, Zhengzhou, China
Local Institution - 0115, Brno, Brno-město, Czechia
Local Institution - 0146, Hradec Králové, Hradec Králové, Czechia
Local Institution - 0041, Prague, Praha 5, Czechia
Centre Antoine-Lacassagne, Nice, Alpes-Maritimes, France
CHU Strasbourg-Hautepierre, Strasbourg, Alsace, France
CHU de Bordeaux Hop St ANDRE, Bordeaux, Aquitaine, France
Centre Leon Berard, Lyon Cedex08, Auvergne-Rhône-Alpes, France
Local Institution - 0258, Brest, Finistère, France
Hôpital Foch, Suresnes, Hauts-de-Seine, France
Local Institution - 0002, Saint-Herblain, Loire-Atlantique, France
Local Institution - 0005, Marseille, Provence-Alpes-Côte d'Azur Region, France
Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne, Clermont-Ferrand, Puy-de-Dôme, France
Local Institution - 0001, Villejuif, Val-de-Marne, France
Hôpital Européen Georges Pompidou, Paris, France
Groupe hospitalier Paris saint Joseph, Paris, Île-de-France Region, France
NCT, Heidelberg, Baden-Wurttemberg, Germany
Studienpraxis Urologie, Nürtingen, Baden-Wurttemberg, Germany
TUM Klinikum, Munich, Bavaria, Germany
Klinikum Nürnberg Nord, Nuremberg, Bavaria, Germany
Caritas-Krankenhaus St. Josef, Regensburg, Bavaria, Germany
Medizinische Hochschule Hannover, Hanover, Lower Saxony, Germany
Universitaetsklinikum Schleswig-Holstein Campus Kiel, Kiel, Schleswig-Holstein, Germany
Universitätsklinikum Jena, Jena, Thuringia, Germany
Charité - Universitaetsmedizin Berlin - Campus Bejnamin Franklin, Berlin, Germany
Universitaetsklinikum Duesseldorf, Düsseldorf, Germany
Krankenhaus Nordwest GmbH, Frankfurt, Germany
Universitaetsklinikum Hamburg-Eppendorf, Hamburg, Germany
Marienhospital Herne, Herne, Germany
Universitaetsklinikum Ulm, Ulm, Germany
Local Institution - 0238, Cork, Ireland
Tallaght University Hospital, Dublin, Ireland
Rabin Medical Center, Petah Tikva, Central District, Israel
Local Institution - 0106, Ẕerifin, Central District, Israel
Hadassah Medical Center, Jerusalem, Jerusalem, Israel
Rambam Health Care Campus, Haifa, Northern District, Israel
A.O.U.C. Policlinico di Bari, Bari, Apulia, Italy
Ospedale San Martino, Genoa, Liguria, Italy
Istituto Nazionale Tumori Regina Elena, Rome, Roma, Italy
Azienda Ospedaliero Universitaria Pisana, Pisa, Tuscany, Italy
Istituto Oncologico Veneto IRCCS, Castelfranco Veneto, Veneto, Italy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
Ospedale San Raffaele, Milan, Italy
Azienda Ospedaliera Universitaria Federico II, Naples, Italy
Azienda Ospedaliero Universitaria di Parma, Parma, Italy
Local Institution - 0183, Kawasaki, Kanagawa, Japan
Local Institution - 0171, Bunkyo-ku, Tokyo, Japan
Local Institution - 0169, Koto-ku, Tokyo, Japan
Local Institution - 0179, Toyoma, Toyama, Japan
Local Institution - 0036, Breda, North Brabant, Netherlands
Local Institution - 0033, Amsterdam, North Holland, Netherlands
Local Institution - 0031, Leeuwarden, Provincie Friesland, Netherlands
Akershus Universitetssykehus, Lørenskog, Akershus, Norway
Sykehuset i Vestfold, Tønsberg, Vestfold, Norway
Sykehuset Østfold Kalnes, Sarpsborg, Østfold fylke, Norway
Centrul de Oncologie "Sfântul Nectarie", Craiova, Dolj, Romania
Institutul Oncologic Cluj, Cluj-Napoca, Romania
Institutul Regional de Oncologie, Iași, Romania
Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona], Spain
Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
Hospital de la Santa Creu i Sant Pau, Barcelona, Catalunya [Cataluña], Spain
Hospital Universitario Ramón y Cajal, Madrid, Madrid, Comunidad de, Spain
Local Institution - 0199, Valencia, Valenciana, Comunitat, Spain
Hospital Infanta Cristina, Badajoz, Spain
Hospital Universitario Reina Sofia, Córdoba, Spain
Hospital General Universitario Gregorio Marañon, Madrid, Spain
Hospital Clinico San Carlos, Madrid, Spain
Hospital Universitario 12 de Octubre, Madrid, Spain
Hospital Universitario Virgen Del Rocio, Seville, Spain
Karolinska Universitetssjukhuset Solna, Solna, Stockholms Län [se-01], Sweden
Sahlgrenska Universitetssjukhuset, Gothenburg, Västra Götalands Län [se-14], Sweden
Local Institution - 0241, Malmö, Sweden
Cantonal Hospital St.Gallen, Sankt Gallen, Canton of St. Gallen, Switzerland
Ospedale Regionale Bellinzona e Valli, Bellinzona, Canton Ticino, Switzerland
Kantonsspital Graubünden, Chur, Switzerland
UniversitätsSpital Zürich, Zurich, Switzerland
Local Institution - 0243, Glasgow, Glasgow City, United Kingdom
St Bartholomew's Hospital, London, London, City of, United Kingdom
Royal Marsden Hospital (Sutton), London, Sutton, United Kingdom
Local Institution - 0230, Sheffield, United Kingdom

View source on ClinicalTrials.gov Contact study team (email)