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Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

Abroad (travel likely)RecruitingPHASE2

Conditions

Head and Neck Squamous Cell Carcinoma · Hypopharyngeal Squamous Cell Carcinoma · Laryngeal Squamous Cell Carcinoma · Nasal Cavity Squamous Cell Carcinoma · Oral Cavity Squamous Cell Carcinoma · Oropharyngeal Squamous Cell Carcinoma · Recurrent Head and Neck Squamous Cell Carcinoma · Recurrent Hypopharyngeal Squamous Cell Carcinoma · Recurrent Laryngeal Squamous Cell Carcinoma · Recurrent Nasal Cavity Squamous Cell Carcinoma · Recurrent Oral Cavity Squamous Cell Carcinoma · Recurrent Oropharyngeal Squamous Cell Carcinoma · Stage III Laryngeal Cancer AJCC v8 · Stage III Lip and Oral Cavity Cancer AJCC v8 · Stage III Nasopharyngeal Carcinoma AJCC v8 · Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 · Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8 · Stage IVA Laryngeal Cancer AJCC v8 · Stage IVA Lip and Oral Cavity Cancer AJCC v8 · Stage IVA Nasopharyngeal Carcinoma AJCC v8 · Stage IVB Laryngeal Cancer AJCC v8 · Stage IVB Lip and Oral Cavity Cancer AJCC v8

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Locations

  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California, United States

    Contact: Study coordinator (Site Public Contact) · ucstudy@uci.edu · 877-827-8839
    Contact: Principal Investigator (Victoria M. Villaflor)

  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States

    Contact: Study coordinator (Site Public Contact) · ucstudy@uci.edu · 877-827-8839
    Contact: Principal Investigator (Victoria M. Villaflor)

  • Emory University Hospital Midtown, Atlanta, Georgia, United States

    Contact: Study coordinator (Site Public Contact) · 888-946-7447
    Contact: Principal Investigator (Jose A. Monteiro de Oliveira Novaes)

  • Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States

    Contact: Study coordinator (Site Public Contact) · Elisemarie.curry@ochsner.org · 504-842-8084
    Contact: Principal Investigator (Daniel Johnson)

  • University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania, United States

    Contact: Study coordinator (Site Public Contact) · 412-647-8073
    Contact: Principal Investigator (Kevin J. Contrera)

  • VCU Massey Comprehensive Cancer Center, Richmond, Virginia, United States

    Contact: Study coordinator (Site Public Contact) · CTOclinops@vcu.edu · 804-628-6430
    Contact: Principal Investigator (Erin R. Alesi)
Study leads

  • Matin Imanguli

    Principal Investigator

    JHU Sidney Kimmel Comprehensive Cancer Center LAO

View source on ClinicalTrials.gov(opens in a new tab)