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A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

IsraelRecruitingPHASE2

Conditions

Lymphoma, Large B-Cell, Diffuse

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Locations
  • Infirmary Cancer Care ( Site 0157), Mobile, Alabama, United States
  • Palo Verde Cancer Specialists ( Site 0105), Glendale, Arizona, United States
  • Genesis Cancer and Blood Institute ( Site 0193), Hot Springs, Arkansas, United States
  • Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0135), Burbank, California, United States
  • City of Hope Comprehensive Cancer Center ( Site 0191), Duarte, California, United States
  • Bass Medical Group ( Site 0123), Walnut Creek, California, United States
  • Rocky Mountain Cancer Centers (RMCC) ( Site 8001), Aurora, Colorado, United States
  • Colorado West Healthcare System-Grand Valley Oncology ( Site 0165), Grand Junction, Colorado, United States
  • Medical Oncology Hematology Consultants (MOHC) ( Site 8007), Newark, Delaware, United States
  • Georgetown University Medical Center ( Site 0117), Washington D.C., District of Columbia, United States
  • Boca Raton Regional Hospital-Lynn Cancer Institute ( Site 0130), Boca Raton, Florida, United States
  • Baptist MD Anderson Cancer Center ( Site 0176), Jacksonville, Florida, United States
  • Mount Sinai Cancer Center ( Site 0140), Miami Beach, Florida, United States
  • Mid Florida Hematology and Oncology Center ( Site 0152), Orange City, Florida, United States
  • Beacon Cancer Care ( Site 0142), Post Falls, Idaho, United States
  • University of Chicago Medical Center ( Site 0126), Chicago, Illinois, United States
  • Illinois Cancer Care ( Site 7005), Peoria, Illinois, United States
  • University of Iowa-Holden Comprehensive Cancer Center ( Site 0139), Iowa City, Iowa, United States
  • Mission Blood & Cancer Care ( Site 0114), Waukee, Iowa, United States
  • Saint Elizabeth Medical Center Edgewood ( Site 0141), Edgewood, Kentucky, United States
  • Baptist Health Hardin ( Site 0154), Elizabethtown, Kentucky, United States
  • Baptist Health Lexington ( Site 0127), Lexington, Kentucky, United States
  • Norton Women's and Children's Hospital-Norton Cancer Institute - St. Matthews ( Site 0185), Louisville, Kentucky, United States
  • Our Lady of the Lake Physician Group-Medical Oncology ( Site 0180), Baton Rouge, Louisiana, United States
  • Ochsner LSU Health - Monroe Medical Center, Family Medicine Clinic ( Site 0209), Monroe, Louisiana, United States
  • Ochsner Clinic Foundation ( Site 0189), New Orleans, Louisiana, United States
  • Louisiana State University Health Sciences Shreveport ( Site 0195), Shreveport, Louisiana, United States
  • Minnesota Oncology Hematology (MNO) ( Site 8004), Burnsville, Minnesota, United States
  • Bozeman Health Deaconess Hospital ( Site 0183), Bozeman, Montana, United States
  • NHO Revive Research Institute, LLC ( Site 0121), Lincoln, Nebraska, United States
  • University Of Nebraska Medical Center ( Site 0110), Omaha, Nebraska, United States
  • Atlantic Health Morristown Medical Center ( Site 0163), Morristown, New Jersey, United States
  • Valley Health Systems - Ridgewood Campus ( Site 0125), Paramus, New Jersey, United States
  • Erie County Medical Center ( Site 0175), Buffalo, New York, United States
  • Roswell Park Cancer Institute ( Site 0192), Buffalo, New York, United States
  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 0208), Mineola, New York, United States
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone ( Site 0108), New York, New York, United States
  • SUNY Upstate Cancer Center ( Site 0178), Syracuse, New York, United States
  • Clinical Research Alliance ( Site 0122), Westbury, New York, United States
  • University of North Carolina Medical Center ( Site 0136), Chapel Hill, North Carolina, United States
  • Novant Health Presbyterian Medical Center ( Site 0177), Charlotte, North Carolina, United States
  • Novant Health Forsyth Medical Center ( Site 0206), Winston-Salem, North Carolina, United States
  • University of Cincinnati Medical Center ( Site 0156), Cincinnati, Ohio, United States
  • University Hospitals of Cleveland ( Site 0155), Cleveland, Ohio, United States
  • Fairview Hospital-Moll Cancer Center ( Site 0198), Cleveland, Ohio, United States
  • Cleveland Clinic Main ( Site 0101), Cleveland, Ohio, United States
  • Cleveland Clinic - Hillcrest Hospital-Hillcrest Hospital Cancer Center ( Site 0199), Mayfield Heights, Ohio, United States
  • Providence Portland Medical Center ( Site 0120), Portland, Oregon, United States
  • Providence Oncology and Hematology Clinic Westside ( Site 0179), Portland, Oregon, United States
  • Alliance Cancer Specialists (ACS) ( Site 8010), Horsham, Pennsylvania, United States
  • Cancer Care Associates Of York ( Site 0174), York, Pennsylvania, United States
  • Medical University of South Carolina ( Site 0153), Charleston, South Carolina, United States
  • Tennessee Cancer Specialists ( Site 7004), Knoxville, Tennessee, United States
  • SCRI Oncology Partners ( Site 7002), Nashville, Tennessee, United States
  • Texas Oncology - West Texas ( Site 8008), Amarillo, Texas, United States
  • Texas Oncology - Central/South Texas ( Site 8006), Austin, Texas, United States
  • Texas Oncology - Northeast Texas ( Site 8002), Palestine, Texas, United States
  • Texas Oncology - San Antonio ( Site 8009), San Antonio, Texas, United States
  • The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( Site 0145), Tyler, Texas, United States
  • Intermountain Medical Center ( Site 0182), Murray, Utah, United States
  • Intermountain Healthcare - St. George ( Site 0203), St. George, Utah, United States
  • Virginia Cancer Specialists, PC ( Site 8003), Manassas, Virginia, United States
  • VCU Health Adult Outpatient Pavillion ( Site 0138), Richmond, Virginia, United States
  • Northwest Cancer Specialists (Compass Oncology) ( Site 8000), Vancouver, Washington, United States
  • SSM Health Dean Medical Group ( Site 0106), Madison, Wisconsin, United States
  • Medical College of Wisconsin ( Site 0103), Milwaukee, Wisconsin, United States
  • AZ Sint-Maarten, Campus Leopoldstraat 2 ( Site 0306), Mechelen, Antwerpen, Belgium
  • Cliniques Universitaires Saint-Luc ( Site 0302), Brussels, Bruxelles-Capitale, Region de, Belgium
  • Hopital de Jolimont ( Site 0304), Haine-Saint-Paul, Hainaut, Belgium
  • UZ Leuven ( Site 0301), Leuven, Vlaams-Brabant, Belgium
  • AZ Delta ( Site 0303), Roeselare, West-Vlaanderen, Belgium
  • Uniklinik Erlangen ( Site 0412), Erlangen, Bavaria, Germany
  • Universitaetsklinikum Wuerzburg ( Site 0401), Würzburg, Bavaria, Germany
  • HELIOS Klinikum Wuppertal ( Site 0435), Wuppertal, North Rhine-Westphalia, Germany
  • Otto-Von-Guericke-Universitaet Magdeburg ( Site 0411), Magdeburg, Saxony-Anhalt, Germany
  • St Vincent's University Hospital ( Site 0502), Dublin, Dublin, Ireland
  • Mater Misercordiae University Hospital ( Site 0501), Dublin, Ireland
  • University Hospital Limerick ( Site 0503), Limerick, Ireland
  • Soroka Medical Center ( Site 0606), Beersheba, Israel
  • Rambam Health Care Campus ( Site 0604), Haifa, Israel
  • Edith Wolfson Medical Center ( Site 0602), Holon, Israel
  • Haddasah Medical Center ( Site 0601), Jerusalem, Israel
  • Rabin Medical Center ( Site 0607), Petah Tikva, Israel
  • Sheba Medical Center ( Site 0603), Ramat Gan, Israel
  • ZIV Medical Center ( Site 0605), Safed, Israel
  • IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 0707), Meldola, Forli-Cesena, Italy
  • Istituto Clinico Humanitas ( Site 0704), Rozzano, Milano, Italy
  • Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo ( Site 0703), Alessandria, Italy
  • Istituto Europeo di Oncologia ( Site 0701), Milan, Italy
  • Universita degli Studi di Napoli Federico II ( Site 0705), Naples, Italy
  • Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO ( Site 0702), Palermo, Italy
  • Arcispedale Santa Maria Nuova ( Site 0706), Reggio Emilia, Italy
  • Aichi Cancer Center ( Site 1007), Nagoya, Aichi-ken, Japan
  • Fujita Health University Hospital ( Site 1003), Toyoake, Aichi-ken, Japan
  • Hokkaido University Hospital ( Site 1004), Sapporo, Hokkaido, Japan
  • National Hospital Organization Sendai Medical Center ( Site 1005), Sendai, Miyagi, Japan
  • Kansai Medical University Hospital ( Site 1006), Hirakata, Osaka, Japan
  • Shimane University Hospital ( Site 1002), Izumo, Shimane, Japan
  • Nippon Medical School Hospital ( Site 1001), Bunkyo, Tokyo, Japan
  • National Cancer Center Hospital ( Site 1009), Chūō, Tokyo, Japan
  • Nagasaki University Hospital ( Site 1008), Nagasaki, Japan
  • Pratia MCM Krakow ( Site 0804), Karkow, Lesser Poland Voivodeship, Poland
  • Szpital Specjalistyczny im. Jedrzeja Sniadeckiego w Nowym Saczu ( Site 0806), Nowy Sącz, Lesser Poland Voivodeship, Poland
  • Specjalistyczny Szpital im. Dr Alfreda Sokolowskiego w Walbrzychu ( Site 0807), Wałbrzych, Lower Silesian Voivodeship, Poland
  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0803), Warsaw, Masovian Voivodeship, Poland
  • Uniwersyteckie Centrum Kliniczne ( Site 0802), Gdansk, Pomeranian Voivodeship, Poland
  • Pratia Onkologia Katowice ( Site 0801), Katowice, Silesian Voivodeship, Poland
  • Bristol Haematology and Oncology Centre ( Site 0908), Bristol, Bristol, City of, United Kingdom
  • Stoke Mandeville Hospital ( Site 0917), Aylesbury, Buckinghamshire, United Kingdom
  • Royal Devon & Exeter Hospital ( Site 0910), Exeter, Devon, United Kingdom
  • University Hospitals Plymouth NHS Trust ( Site 0905), Plymouth, Devon, United Kingdom
  • The James Cook University Hospital ( Site 0909), Middlesbrough, England, United Kingdom
  • Lincoln County Hospital ( Site 0906), Lincoln, Lincolnshire, United Kingdom
  • Guy s & St Thomas NHS Foundation Trust ( Site 0904), London, London, City of, United Kingdom
  • Hammersmith Hospital ( Site 0915), London, London, City of, United Kingdom
  • Churchill Hospital ( Site 0903), Oxford, Oxfordshire, United Kingdom
  • Queen Elizabeth Hospital Birmingham ( Site 0912), Birmingham, United Kingdom
  • Clatterbridge Cancer Centre - Liverpool ( Site 0911), Liverpool, United Kingdom
  • Christie Hospital NHS Trust ( Site 0901), Manchester, United Kingdom
View source on ClinicalTrials.gov(opens in a new tab)Contact study team (email)