Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

Yale Cancer Center, New Haven, Connecticut, United States

Orchard Healthcare Research Inc., Skokie, Illinois, United States

University of Kansas Medical Center Research Institute, Inc., Kansas City, Kansas, United States

Maryland Oncology Hematology, P.A., Silver Spring, Maryland, United States

Tufts Medical Center, Boston, Massachusetts, United States

University of Michigan Comprehensive Cancer Center Michigan Medicine, Ann Arbor, Michigan, United States

Minnesota Oncology Hematology, P.A., Minneapolis, Minnesota, United States

Memorial Sloan Kettering Cancer Center - MAIN, New York, New York, United States

Montefiore Medical Center, The Bronx, New York, United States

Providence Portland Medical Center, Portland, Oregon, United States

Penn State University Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

Prisma Health Cancer Institute, ITOR, CRU, Greenville, South Carolina, United States

Tennessee Oncology Nashville Midtown, Nashville, Tennessee, United States

UT Southwestern Medical Center, Dallas, Texas, United States

Texas Oncology, P.A. - Tyler, Tyler, Texas, United States

Virginia Oncology Associates, Norfolk, Virginia, United States

Blue Ridge Cancer Care, Roanoke, Virginia, United States

Wenatchee Valley Hospital & Clinics, Wenatchee, Washington, United States

CEMIC Ciudad Autonoma, Buenos Aires, Argentina

Instituto Medico Especializado Alexander Fleming, Buenos Aires, Argentina

Clinica Universitaria Privada Reina Fabiola, Córdoba, Argentina

Centro de Investigaciones Medicas Mar del Plata, Mar del Plata, Argentina

Instituto Medico de la Fundacion Estudios Clinicos, Rosario, Argentina

Flinders Medical Centre, Bedford Park, Australia

Monash Medical Centre Clayton, Clayton, Australia

Townsville University Hospital, Douglas, Australia

Peter MacCallum Cancer Centre, North Melbourne, Australia

GenesisCare North Shore (Oncology), St Leonards, Australia

St John of God Subiaco Hospital, Subiaco, Australia

Wollongong Hospital, Wollongong, Australia

LKH - Universitaetsklinikum Graz, Graz, Austria

Medizinische Universität Innsbruck, Innsbruck, Austria

Medizinische Universität Wien, Vienna, Austria

St. Josef Krankenhaus Wien, Vienna, Austria

Landesklinikum Wiener Neustadt, Wiener Neustadt, Austria

Institut Jules Bordet, Anderlecht, Belgium

AZ Sint-Lucas, Bruges, Belgium

Cliniques Universitaires Saint-Luc, Brussels, Belgium

UZ Leuven, Leuven, Belgium

Centre Hospitalier Universitaire de Liege, Liège, Belgium

CHU UCL Namur, Namur, Belgium

Centro de Oncologia - Unidade Brasilia - Hospital Sirio Libanes, Brasília, Brazil

ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira Sao Paulo, Brazil, Brazil

CEPON - Centro de Pesquisas Oncológicas de Santa Catarina, Florianópolis, Brazil

Fundação Doutor Amaral Carvalho, Jaú, Brazil

Liga Norte-Rio-Grandense Contra o Câncer, Natal, Brazil

Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil

Hospital São Lucas da PUCRS, Porto Alegre, Brazil

IMIP - Instituto de Medicina Integral Professor Fernando Figueira, Recife, Brazil

Hospital das Clínicas FMRP-USP, Ribeirão Preto, Brazil

INCA - Instituto Nacional de Câncer, Rio de Janeiro, Brazil

Obras Sociais Irmã Dulce - Hospital Santo Antônio, Salvador, Brazil

Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto, Sao Jose Rio Preto, Brazil

Cité de la Santé de Laval, Laval, Canada

Trillium Health Partners Credit Valley Hospital, Mississauga, Canada

St. Mary's Hospital, Montreal, Canada

CHUS - Hôtel-Dieu, Sherbrooke, Canada

Mount Sinai Hospital, Toronto, Canada

Mount Sinai Hospital, Toronto, Canada

Sunnybrook Health Sciences Centre, Toronto, Canada

University Health Network - Princess Margaret Cancer Centre, Toronto, Canada

Biocenter, Concepción, Chile

URUMED Spa, Rancagua, Chile

Centro de Investigacion del Maule, Region Del Maule, Chile

Centro de Estudios Clinicos SAGA, Santiago, Chile

FALP - Fundación Arturo López Pérez, Santiago, Chile

Hospital Clinico Universidad de Chile, Santiago, Chile

Beijing Cancer Hospital, Beijing, China

Peking University Third Hospital, Beijing, China

The First People's Hospital of Changzhou, Changzhou, China

Fujian Cancer Hospital, Fuzhou, China

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China

The First Affiliated Hospital of Zhejiang University school of medicine, Hangzhou, China

Harbin Medical University Cancer Hospital, Harbin, China

Anhui Provincial Cancer Hospital, Hefei, China

Shandong Cancer Hospital, Jinan, China

Gansu Provincial Cancer Hospital, Lanzhou, China

Lanzhou University Second Hospital, Lanzhou, China

Linyi Cancer Hospital, Linyi, China

Meizhou People's Hospital, Meizhou, China

Liaoning Cancer Hospital & Institute, Shenyang, China

The Second Affiliated Hospital of Soochow University, Suzhou, China

Shanxi Provincial Cancer Hospital, Taiyuan, China

Shanxi Provincial People's Hospital, Taiyuan, China

Tianjin Medical University Cancer Institute & Hospital, Tianjin, China

The Affiliated Cancer Hospital of Xinjiang Medical university, Ürümqi, China

Hubei Cancer Hospital, Wuhan, China

Wuxi 4th People's Hospital, Wuxi, China

The First Affiliated Hospital of Xian Jiaotong University, Xi'an, China

The First Affiliated Hospital of Xiamen University, Xiamen, China

Fudan University Shanghai Cancer Center, Xuhui District, China

Xuzhou Central Hospital, Xuzhou, China

General Hospital of Ningxia Medical University, Yinchuan, China

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China

Masarykuv onkologicky ustav, Brno, Czechia

Fakultni nemocnice Hradec Kralove, Hradec Králové, Czechia

Fakultni nemocnice Olomouc, Olomouc, Czechia

Fakultni nemocnice v Motole, Prague, Czechia

Institut Sainte Catherine, Avignon, France

CHU de Brest - Hopital de la Cavale Blanche, Brest, France

Centre Georges François Leclerc, Dijon, France

CHU Grenoble - Hopital Michallon, Grenoble, France

Centre Oscar Lambret, Lille, France

Hopital Prive Jean Mermoz, Lyon, France

CHU Montpellier, Saint Eloi, Montpellier, France

Chru De Nantes Hotel-Dieu, Nantes, France

Hôpital Européen Georges Pompidou, Paris, France

Hôpital Saint-Antoine, Paris, France

Institut Mutualiste Montsouris, Paris, France

CHU Bordeaux - Hôpital Haut-Lévêque, Pessac, France

CHU Poitiers - Hôpital la Milétrie, Poitiers, France

Institut de Cancérologie de Strasbourg Europe - ICANS, Strasbourg, France

Hôpital Foch, Suresnes, France

Hopital Rangueil, Toulouse, France

Charité Universitätsmedizin Berlin - Campus Virchow-Klinikum, Berlin, Germany

Vivantes Klinikum im Friedrichshain, Berlin, Germany

Klinikum Chemnitz gGmbH, Chemnitz, Germany

Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Germany

Universitaetsklinikum Frankfurt Goethe-Universitaet, Frankfurt am Main, Germany

Universitaetsklinikum Hamburg-Eppendorf, Hamburg, Germany

Universitaetsklinikum Heidelberg, Heidelberg, Germany

Universitaetsklinikum Leipzig AoeR, Leipzig, Germany

Klinikum rechts der Isar der TU Muenchen, München, Germany

Presidio Ospedaliero Garibaldi Nesima, Catania, Italy

Azienda Ospedaliera Universitaria Careggi, Florenze, Italy

IRCCS Ospedale Policlinico San Martino, Genova, Italy

Azienda Socio Sanitaria Territoriale Niguarda (Grande Ospedale Metropolitano Niguarda), Milan, Italy

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

Ospedale San Raffaele, Milan, Italy

A.O.U. Policlinico di Modena, Modena, Italy

Azienda Ospedaliera Universitaria- Università degli Studi della Campania "Luigi Vanvitelli", Naples, Italy

IOV - Istituto Oncologico Veneto IRCCS, Padova, Italy

Azienda Ospedaliero Universitaria Pisana, Pisa, Italy

Azienda Unità Sanitaria Locale- Ravenna, Ravenna, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

Istituto Clinico Humanitas, Rozzano, Italy

IRCCS Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy

Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Italy

Azienda Ospedaliera Card. G. Panico, Tricase, Italy

Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital, Bunkyō City, Japan

National Cancer Center Hospital, Chūōku, Japan

Gifu University Hospital, Gifu, Japan

Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan

National Cancer Center Hospital East, Kashiwa-shi, Japan

JCHO Kyushu Hospital, Kitakyushu, Japan

Kochi Health Sciences Center, Kochi, Japan

Cancer Institute Hospital of JFCR, Kōtoku, Japan

NHO Shikoku Cancer Center, Matsuyama, Japan

Aichi Cancer Center Hospital, Nagoya, Japan

Miyagi Cancer Center, Natori-shi, Japan

Niigata Cancer Center Hospital, Niigata, Japan

Osaka International Cancer Institute, Osaka, Japan

Kindai University Hospital, Osakasayama-shi, Japan

Hokkaido University Hospital, Sapporo, Japan

Osaka University Hospital, Suita-shi, Japan

Kanagawa Cancer Center, Yokohama, Japan

Antoni van Leeuwenhoek, Amsterdam, Netherlands

Medisch Centrum Leeuwarden, Leeuwarden, Netherlands

Radboudumc, Nijmegen, Netherlands

Erasmus Medisch Centrum, Rotterdam, Netherlands

ETZ Elisabeth, Tilburg, Netherlands

UMC Utrecht, Utrecht, Netherlands

Haukeland University Hospital, Bergen, Norway

Akershus universitetssykehus HF, Lørenskog, Norway

Oslo Universitetssykehus HF, Ullevål, Oslo, Norway

St. Olavs Hospital Hf, Universitetssykehuset i Trondheim, Trondheim, Norway

Beskidzkie Centrum Onkologii im.Jana Pawla II, Bielsko-Biala, Poland

Szpital Wojewodzki im. Mikolaja Kopernika, Koszalin, Poland

Wielkopolskie Centrum Onkologii, Poznan, Poland

Narodowy Instytut Onkologii im. Marii Sklodowskiej Curie Panstwowy Instytut Badawczy W Warszawie, Warsaw, Poland

Warszawski Uniwersytet Medyczny, Warsaw, Poland

Hospital de Braga, Braga, Portugal

Hospital da Senhora da Oliveira Guimarães, E.P.E., Guimarães, Portugal

Fundação Champalimaud, Lisbon, Portugal

Hospital da Luz, Lisbon, Portugal

Unidade Local de Saúde de Santa Maria, E.P.E. - Hospital de Santa Maria, Lisbon, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil, EPE, Porto, Portugal

Institutul Clinic Fundeni, Bucharest, Romania

Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj Napoca, Cluj-Napoca, Romania

S.C Medisprof S.R.L, Cluj-Napoca, Romania

Centrul de Oncologie Sfantul Nectarie Craiova, Craiova, Romania

Institutul Regional de Oncologie Iasi, Iași, Romania

S.C Ovidius Clinical Hospital S.R.L, Ovidiu, Romania

S.C. Sigmedical Services SRL, Suceava, Romania

Chungbuk National University Hospital, Cheongju-si, South Korea

Kyungpook National University Chilgok Hospital, Daegu, South Korea

National Cancer Center, Goyang-si, South Korea

Chonnam National University Hwasun Hospital, Hwasun-gun, South Korea

Gachon University Gil Medical Center, Incheon, South Korea

Jeonbuk national university hospital, Jeonju, South Korea

Seoul National University Bundang Hospital, Seongnam, South Korea

CHA Bundang Medical Center, CHA University, Seongnam-si, South Korea

Korea University Anam Hospital, Seoul, South Korea

Seoul National University Hospital, Seoul, South Korea

Severance Hospital, Yonsei University Health System, Seoul, South Korea

Asan Medical Center, Seoul, South Korea

Samsung Medical Center, Seoul, South Korea

The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea

ICO Badalona - Hospital Universitari Germans Trias i Pujol, Badalona, Spain

Hospital Clinic de Barcelona, Barcelona, Spain

Hospital del Mar, Barcelona, Spain

Hospital Universitari Vall d'Hebron, Barcelona, Spain

Hospital Universitario Reina Sofia, Córdoba, Spain

Hospital General Universitario de Elche, Elche, Spain

ICO l'Hospitalet - Hospital Duran i Reynals, L'Hospitalet de Llobregat, Spain

Hospital General Universitario Gregorio Marañon, Madrid, Spain

Hospital Universitario La Paz, Madrid, Spain

Hospital Universitario Ramon y Cajal, Madrid, Spain

MD Anderson Cancer Centre, Madrid, Spain

Hospital Regional Universitario de Malaga, Málaga, Spain

Hospital General Universitario Morales Meseguer, Murcia, Spain

Hospital Universitario Central de Asturias, Oviedo, Spain

Hospital Universitario de Navarra, Pamplona, Spain

Hospital Universitario Virgen del Rocio, Seville, Spain

Hospital Clinico Universitario de Valencia, Valencia, Spain

Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Taiwan

National Cheng Kung University Hospital, Tainan, Taiwan

Taipei Veterans General Hospital, Taipei, Taiwan

National Taiwan University Hospital, Taipei, Taiwan

Chang Gung Memorial Hospital,Linkou, Taoyuan City, Taiwan

Siriraj Hospital, Bangkoknoi, Thailand

Vajira Hospital, Dusit, Thailand

Songklanagarind Hospital, Hat Yai, Thailand

Chulabhorn Hospital, Laksi, Thailand

King Chulalongkorn Memorial Hospital, Pathum Wan, Thailand

Medical Park Seyhan Hospital, Adana, Turkey (Türkiye)

Ankara City Hospital, Ankara, Turkey (Türkiye)

Dr. Abdurrahman Yurtaslan Oncology Teaching and Research Hospital, Ankara, Turkey (Türkiye)

Hacettepe University Medical Faculty, Ankara, Turkey (Türkiye)

Dicle University, Medical faculty, Diyarbakır, Turkey (Türkiye)

Ataturk University Medical Faculty, Erzurum, Turkey (Türkiye)

Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkey (Türkiye)

Medipol University Medical Faculty, Istanbul, Turkey (Türkiye)

İ.E.Ü. Medicalpoint İzmir Hastanesi, Izmir, Turkey (Türkiye)

Medical Park Samsun Hastanesi, Samsun, Turkey (Türkiye)

Queen Elizabeth Hospital, Birmingham, United Kingdom

Velindre Cancer Centre, Cardiff, United Kingdom

Ninewells Hospital, Dundee, United Kingdom

Castle Hill Hospital, Hull, United Kingdom

St James's University Hospital, Leeds, United Kingdom

Sarah Cannon Research Institute UK, London, United Kingdom

University College London Hospitals, London, United Kingdom

Altnagelvin Area Hospital, Londonderry, United Kingdom

The Christie Hospital, Manchester, United Kingdom

Royal Marsden Hospital, Sutton, United Kingdom

Hanoi Oncology hospital, Hanoi, Vietnam

National Cancer Hospital, Hanoi, Vietnam

Cho Ray Hospital, Ho Chi Minh City, Vietnam

HCMC Oncology Hospital, Ho Chi Minh City, Vietnam

HCMC University Medical Center, HoChiMinh, Vietnam