A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Israel

RecruitingPHASE3

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Conditions

Colorectal Neoplasms

Locations

Banner MD Anderson Cancer Center, Gilbert, Arizona, United States
St. Bernard's Medical Center, Jonesboro, Arkansas, United States
Highlands Oncology Group, Springdale, Arkansas, United States
CBCC Global Research, Bakersfield, California, United States
Los Angeles Cancer Network, Glendale, California, United States
Cancer and Blood Specialty Clinic, Los Alamitos, California, United States
USC Norris Comprehensive Cancer Center, Los Angeles, California, United States
UCLA, Santa Monica, California, United States
Providence Medical Foundation, Santa Rosa, California, United States
Torrance Memorial Physicians Network, Torrance, California, United States
Rocky Mountain Cancer Centers, Denver, Colorado, United States
Yale University School Of Medicine, New Haven, Connecticut, United States
Georgetown Univ Medical Center Lombardi Cancer Center, Washington D.C., District of Columbia, United States
Florida Cancer Specialists South, Fort Myers, Florida, United States
AdventHealth Medical Group Oncology and Hematology at Orlando, Orlando, Florida, United States
Florida Cancer Specialists North Region, St. Petersburg, Florida, United States
Florida Cancer Specialists East, West Palm Beach, Florida, United States
Grady Memorial Hospital, Atlanta, Georgia, United States
Winship Cancer Institute Emory University, Atlanta, Georgia, United States
Illinois CancerCare, Peoria, Illinois, United States
Fort Wayne Medical Oncology & Hematology, Fort Wayne, Indiana, United States
University of Iowa Hospital, Iowa City, Iowa, United States
Mission Cancer Blood, Waukee, Iowa, United States
Cancer Center of Kansas, Wichita, Kansas, United States
Ochsner Clinic Foundation, New Orleans, Louisiana, United States
MedStar Franklin Square Medical Center, Baltimore, Maryland, United States
VA Ann Arbor Healthcare System, Ann Arbor, Michigan, United States
University of Michigan, Ann Arbor, Michigan, United States
Henry Ford Hospital, Detroit, Michigan, United States
Start Midwest, Grand Rapids, Michigan, United States
Hattiesburg Clinic, Hattiesburg, Mississippi, United States
Washington University School Of Medicine, St Louis, Missouri, United States
Nebraska Cancer Specialists Midwest Cancer Center, Omaha, Nebraska, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
Astera Cancer Care, East Brunswick, New Jersey, United States
Rutgers Cancer Institute, New Brunswick, New Jersey, United States
University of New Mexico Cancer Center, Albuquerque, New Mexico, United States
Perlmutter Cancer Center at NYU Long Island, Mineola, New York, United States
Mount Sinai, New York, New York, United States
Mount Sinai West, New York, New York, United States
NYU Langone Medical Center NYU Hematology Associates, New York, New York, United States
Herbert Irving Comprehensive Cancer Center Columbia University Medical Center, New York, New York, United States
New York Cancer and Blood Specialists, Shirley, New York, United States
Montefiore Einstein Comprehensive Cancer Center, The Bronx, New York, United States
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
Gabrail Cancer Center, Canton, Ohio, United States
University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
Cleveland Clinic Cancer Center Fairview Hospital Moll Pavilion, Cleveland, Ohio, United States
Taussig Cancer Insititute Cleveland Clinic, Cleveland, Ohio, United States
Cleveland Clinic Cancer Center Independence Family Health Center, Independence, Ohio, United States
Cleveland Clinic Cancer Center Mansfield, Mansfield, Ohio, United States
Cleveland Clinic Cancer Center Hillcrest Hospital, Mayfield Heights, Ohio, United States
Cleveland Clinic Cancer Centers Sandusky, Sandusky, Ohio, United States
Cleveland Clinic Cancer Center Strongsville, Strongsville, Ohio, United States
Cleveland Clinic Cancer Center South Pointe Hospital, Warrensville Heights, Ohio, United States
Wooster Milltown Specialty and Surgery Center, Wooster, Ohio, United States
Oregon Health And Science University, Portland, Oregon, United States
Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
University Of Pittsburgh Medical Center UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
SCRI Oncology Partners, Nashville, Tennessee, United States
Texas Oncology West Texas, Abilene, Texas, United States
Texas Oncology DFW, Dallas, Texas, United States
UT Southwestern, Dallas, Texas, United States
MD Anderson Cancer Center, Houston, Texas, United States
Texas Oncology - San Antonio, San Antonio, Texas, United States
Baylor Scott and White Health, Temple, Texas, United States
Virginia Cancer Specialists, Arlington, Virginia, United States
Inova Schar Cancer Institute Dept of Fairfax Hospital, Fairfax, Virginia, United States
Richmond VA Medical Center, Richmond, Virginia, United States
VCU Massey Comprehensive Cancer Center, Richmond, Virginia, United States
Swedish Cancer Institute Edmonds, Edmonds, Washington, United States
Swedish Cancer Institute Issaquah, Issaquah, Washington, United States
Swedish Cancer Institute, Seattle, Washington, United States
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
William S. Middleton Memorial VA, Madison, Wisconsin, United States
Institut Jules Bordet, Anderlecht, Belgium
Universitair Ziekenhuis Antwerpen, Edegem, Belgium
AZ Maria Middelares, Ghent, Belgium
Hopital de Jolimont, Haine Saint Paul La Louviere, Belgium
Az Groeninge, Kortrijk, Belgium
Universitair Ziekenhuis Leuven, Leuven, Belgium
Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman, Liège, Belgium
Fundacao Pio XII, Barretos, Brazil
Fundacao Universidade de Caxias do Sul, Caxias do Sul, Brazil
Fundacao Doutor Amaral Carvalho, Jaú, Brazil
Hospital Nossa Senhora da Conceicao S A, Porto Alegre, Brazil
Hospital Santa Izabel Santa Casa de Misericordia da Bahia, Salvador, Brazil
Clinica de Hematologia e Oncologia Viver Ltda, Santa Maria, Brazil
Fundacao Faculdade Regional De Medicina S Jose Rio Preto Hospital De Base, São José do Rio Preto, Brazil
Fundacao Faculdade de Medicina - Instituto do Cancer do Estado de Sao Paulo, São Paulo, Brazil
Fundacao Antonio Prudente A C Camargo Cancer Center, São Paulo, Brazil
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, São Paulo, Brazil
Associacao Feminina de Educacao e Combate ao Cancer Hospital Santa Rita de Cassia, Vitória, Brazil
Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta, Canada
Ottawa Hospital, Ottawa, Ontario, Canada
Princess Margaret Cancer Centre, Toronto, Ontario, Canada
Centre de Recherche du CHUM, Montreal, Quebec, Canada
Peking University First Hospital, Beijing, China
Beijing Friendship Hospital Capital Medical University, Beijing, China
Beijing Cancer Hospital, Beijing, China
Peking University Third Hospital, Beijing, China
The First Bethune Hospital of Jilin University, Changchun, China
Hunan Cancer hospital, Changsha, China
Sun Yat Sen University Cancer Center, Guangzhou, China
The Sixth Affiliated Hospital Sun Yat sen University, Guangzhou, China
Guangdong Provincial People's Hospital, Guangzhou, China
The First Affiliated Hospital Zhejiang University College of Medicine, Hangzhou, China
The Second Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou, China
Zhejiang Cancer Hospital, Hangzhou, China
Harbin medical university cancer hospital, Harbin, China
Huizhou Central People's Hospital, Huizhou, China
The First Affiliated Hospital of NanChang University, Nanchang, China
Fudan University Shanghai Cancer Center, Shanghai, China
Liaoning Cancer Hospital and Institute, Shenyang, China
Peking University Shenzhen Hospital, Shenzhen, China
West China Hospital of Sichuan University, Sichuan, China
First Hospital of Shanxi Medical University, Taiyuan, China
Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
Hubei Cancer Hospital, Wuhan, China
Institut Sainte Catherine, Avignon, France
Hopital Claude Huriez, Lille, France
Hopital Prive Jean Mermoz, Lyon, France
Institut du Cancer de Montpellier, Montpellier, France
CHU Nantes, Nantes, France
Hopital Saint Antoine, Paris, France
Hopital Haut Leveque, Pessac, France
CHU De Poitiers, Poitiers, France
Gustave Roussy, Villejuif, France
Charite Universitatsmedizin Berlin Campus Virchow Klinikum, Berlin, Germany
Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Germany
Essen University Hospital, Essen, Germany
Krankenhaus NorthWest, Frankfurt am Main, Germany
Praxis fur interdisziplinare Onkologie & Hamatologie GbR, Freiburg im Breisgau, Germany
Asklepios Klinik Altona, Hamburg, Germany
National Center for Tumor Diseases NCT, Heidelberg, Germany
Universitatsmedizin der Johannes Gutenberg Universitat Mainz, Mainz, Germany
Klinikum der Universitaet Muenchen, Munich, Germany
Universitatsklinikum Ulm, Ulm, Germany
Semmelweis Egyetem, Budapest, Hungary
Markhot Ferenc Oktatokorhaz es Rendelointezet, Eger, Hungary
Pecsi Tudomanyegyetem, Pécs, Hungary
Szegedi Tudomanyegyetem, Szeged, Hungary
Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India
B P Poddar Hospital and Medical research Limited, Kolkata, India
Tata Memorial Hospital, Mumbai, India
Deenanath Mangeshkar Hospital and Research Centre, Pune, India
Mahamana Pandit Madan Mohan Malviya Cancer Centre, Varanasi, India
Yitzhak Shamir Medical Center, Beer Yaakov, Israel
Rambam Medical Center, Haifa, Israel
Hadassah University Hospita Ein Kerem, Jerusalem, Israel
Rabin Medical Center, Petah Tikva, Israel
Sheba Medical Center, Ramat Gan, Israel
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Assuta MC, Tel Aviv, Israel
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy
Istituto Dei Tumori Di Milano, Milan, Italy
Istituto Oncologico Veneto - IRCCS, Padova, Italy
Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
Istituto Clinico Humanitas, Rozzano, Italy
Chiba Cancer Center, Chiba, Japan
National Cancer Center Hospital, Chūōku, Japan
National Cancer Center Hospital East, Kashiwa, Japan
Aichi Cancer Center, Nagoya, Japan
National Hospital Organization Osaka National Hospital, Osaka, Japan
Osaka International Cancer Institute, Osaka, Japan
Shizuoka Cancer Center, Shizuoka, Japan
The University of Osaka Hospital, Suita, Japan
The Cancer Institute Hospital of JFCR, Tokyo, Japan
Hospital Canselor Tuanku Muhriz UKM, Cheras, Malaysia
Hospital Pulau Pinang, George Town, Malaysia
Hospital Raja Permaisuri Bainun, Ipoh, Malaysia
Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
University Malaya Medical Centre, Kuala Lumpur, Malaysia
Hospital Umum Sarawak, Kuching, Malaysia
National Cancer Institute, Putrajaya, Malaysia
Meander Medisch Centrum, Amersfoort, Netherlands
Antoni van Leeuwenhoek, Amsterdam, Netherlands
Radboud University Medical Center, Nijmegen, Netherlands
Erasmus MC, Rotterdam, Netherlands
Elisabeth-TweeSteden Ziekenhuis, Tilburg, Netherlands
UMC Utrecht, Utrecht, Netherlands
Bialostockie Centrum Onkologii im Marii Sklodowskiej Curie w Bialymstoku, Bialystok, Poland
Wojewodzki Szpital Specjalistyczny, Biała Podlaska, Poland
Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza, Brzozów, Poland
Uniwersyteckie Centrum Kliniczne, Gdansk, Poland
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz w Gliwicach, Gliwice, Poland
Instytut Centrum Zdrowia Matki Polki, Lodz, Poland
Szpital Kliniczny MSWiA z WMCO, Olsztyn, Poland
SPZOZ Opolskie Centrum Onkologii im. Prof. Tadeusza Koszarowskiego, Opole, Poland
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy, Warsaw, Poland
Pan American Center for Oncology Trials LLC, Barrio Monacillos, Puerto Rico
Kyungpook National University Chilgok Hospital, Daegu, South Korea
Seoul National University Hospital, Seoul, South Korea
Severance Hospital Yonsei University Health System, Seoul, South Korea
Asan Medical Center, Seoul, South Korea
Samsung Medical Center, Seoul, South Korea
The Catholic University of Korea Seoul St Marys Hospital, Seoul, South Korea
Hosp. de La Santa Creu I Sant Pau, Barcelona, Spain
Hosp Univ Vall D Hebron, Barcelona, Spain
Hosp. Gral. Univ. Gregorio Maranon, Madrid, Spain
Hosp. Univ. Ramon Y Cajal, Madrid, Spain
Hosp. Univ. 12 de Octubre, Madrid, Spain
Clinica Univ. de Navarra, Pamplona, Spain
Hosp. Virgen Del Rocio, Seville, Spain
Hosp. Clinico Univ. de Valencia, Valencia, Spain
Sahlgrenska University Hospital, Gothenburg, Sweden
Skanes universitetssjukhus, Lund, Sweden
Sodersjukhuset, Stockholm, Sweden
Karolinska Universitetssjukhuset, Stockholm, Sweden
Uppsala University, Uppsala, Sweden
Kaohsiung Medical University Chung Ho Memorial Hospital, Kaohsiung City, Taiwan
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Taiwan
National Cheng Kung University Hospital, Tainan, Taiwan
National Taiwan University Hospital, Taipei, Taiwan
Linkou Chang Gung Memorial Hospital, Taoyuan District, Taiwan
Adana City Hospital, Adana, Turkey (Türkiye)
Gulhane Egitim ve Arastirma Hastanesi, Ankara, Turkey (Türkiye)
Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey (Türkiye)
Gazi Universitesi Hastanesi, Ankara, Turkey (Türkiye)
Ankara Bilkent Sehir Hastanesi, Ankara, Turkey (Türkiye)
Bakirkoy Training and Research Hospital, Istanbul, Turkey (Türkiye)
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi, Istanbul, Turkey (Türkiye)
Necmettin Erbakan Universitesi Tip Fakultesi Hastanesi, Konya, Turkey (Türkiye)
Sakarya University Training and Research Hospital, Sakarya, Turkey (Türkiye)
Birmingham Heartlands Hospital, Birmingham, United Kingdom
Addenbrooke's Hospital, Cambridge, United Kingdom
Western General Hospital, Edinburgh, United Kingdom
Castle Hill Hospital, Hull, United Kingdom
St James University Hospital, Leeds, United Kingdom
St Bartholomew's Hospital, London, United Kingdom
University College Hospital, London, United Kingdom
Mount Vernon Cancer Centre, Northwood, United Kingdom
Royal Marsden Hospital (Sutton), Sutton, United Kingdom

View source on ClinicalTrials.gov Contact study team (email)