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A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Israel
RecruitingPHASE3

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Conditions

Atopic Dermatitis

Locations
  • Applied Research Center Of Arkansas /ID# 268547, Little Rock, Arkansas, United States
  • Stanford University School of Medicine - Palo Alto /ID# 269622, Palo Alto, California, United States
  • Integrative Skin Science and Research /ID# 265108, Sacramento, California, United States
  • Clearlyderm Dermatology - West Boca /ID# 266323, Boca Raton, Florida, United States
  • Pediatric Skin Research /ID# 266308, Coral Gables, Florida, United States
  • Neoclinical Research - Hialeah /ID# 269694, Hialeah, Florida, United States
  • Cleaver Medical Group Dermatology /ID# 265099, Dawsonville, Georgia, United States
  • Aeroallergy Research Laboratory /ID# 267247, Savannah, Georgia, United States
  • Treasure Valley Medical Research /ID# 266838, Boise, Idaho, United States
  • Northwestern University Feinberg School of Medicine /ID# 265117, Chicago, Illinois, United States
  • Sneeze Wheeze & Itch Associates /ID# 267238, Normal, Illinois, United States
  • Dawes Fretzin, LLC /ID# 265097, Indianapolis, Indiana, United States
  • Equity Medical, LLC /ID# 268270, Bowling Green, Kentucky, United States
  • Maryland Allergy & Asthma Center /ID# 268032, Lanham, Maryland, United States
  • DermAssociates - Rockville /ID# 266457, Rockville, Maryland, United States
  • Washington University School of Medicine - St. Louis /ID# 268545, St Louis, Missouri, United States
  • Skin Specialists /ID# 266331, Omaha, Nebraska, United States
  • DOCS Clinical Research - Canal Winchester /ID# 268271, Canal Winchester, Ohio, United States
  • Wright State Physicians Health Center /ID# 268841, Fairborn, Ohio, United States
  • Oregon Health and Science University /ID# 266483, Portland, Oregon, United States
  • Medical University of South Carolina /ID# 265113, Charleston, South Carolina, United States
  • International Clinical Research - Tennessee /ID# 268548, Murfreesboro, Tennessee, United States
  • Arlington Research Center, Inc /ID# 266330, Arlington, Texas, United States
  • 3A Research - East location /ID# 267622, El Paso, Texas, United States
  • Prime Clinical Research - Mansfield - East Broad Street /ID# 268042, Mansfield, Texas, United States
  • Texas Dermatology and Laser Specialists /ID# 267249, San Antonio, Texas, United States
  • Progressive Clinical Research - San Antonio /ID# 267262, San Antonio, Texas, United States
  • Jordan Valley Dermatology & Research Center /ID# 267092, South Jordan, Utah, United States
  • West Virginia University Hospitals /ID# 265114, Morgantown, West Virginia, United States
  • Wisconsin Medical Center /ID# 267236, Milwaukee, Wisconsin, United States
  • Sanatorio 9 de Julio /ID# 267678, San Miguel de Tucumán, Tucumán Province, Argentina
  • Conexa Investigacion Clinica /ID# 268728, Buenos Aires, Argentina
  • Instituto de Neumonología y Dermatología /ID# 266146, Buenos Aires, Argentina
  • Psoriahue - Buenos Aires /ID# 267737, Buenos Aires, Argentina
  • The Children's Hospital at Westmead /ID# 265430, Westmead, New South Wales, Australia
  • Monash Health - Monash Medical Centre /ID# 267149, Clayton, Victoria, Australia
  • Institute for Skin, Health and Immunity /ID# 266158, Mitcham, Victoria, Australia
  • Medizinische Universitaet Graz /ID# 262741, Graz, Styria, Austria
  • Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 265427, Salzburg, Austria
  • Medizinische Universitaet Wien /ID# 265417, Vienna, Austria
  • Irmandade da Santa Casa de Misericórdia de Porto Alegre /ID# 267455, Porto Alegre, Rio Grande do Sul, Brazil
  • Hospital e Maternidade Celso Pierro - PUC-Campinas /ID# 266965, Campinas, São Paulo, Brazil
  • Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto /ID# 266964, Ribeirão Preto, São Paulo, Brazil
  • Clinica de Alergia Martti Antila /ID# 266197, Sorocaba, São Paulo, Brazil
  • Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao /ID# 266667, São Paulo, Brazil
  • UMHAT Alexandrovska EAD /ID# 265256, Sofiya, Sofia, Bulgaria
  • Medical Center Cordis /ID# 265250, Pleven, Bulgaria
  • Dermatology Research Institute - Blackfoot Trail /ID# 266744, Calgary, Alberta, Canada
  • Rejuvenation Dermatology - Edmonton Downtown /ID# 267871, Edmonton, Alberta, Canada
  • British Columbia Children and Women's Hospital and Health Centre /ID# 265395, Vancouver, British Columbia, Canada
  • Maritime Dermatology /ID# 267359, Halifax, Nova Scotia, Canada
  • Leader Research /ID# 266745, Hamilton, Ontario, Canada
  • Triple A Lab Inc /ID# 266615, Hamilton, Ontario, Canada
  • Lynderm Research Inc /ID# 267006, Markham, Ontario, Canada
  • Allergy Research Canada /ID# 270230, Niagara Falls, Ontario, Canada
  • DermAtelier on Avenue /ID# 267850, Toronto, Ontario, Canada
  • Centre Hospitalier Universitaire (CHU) Sainte-Justine /ID# 266831, Montreal, Quebec, Canada
  • Clinica Dermacross /ID# 266309, Vitacura, Region Metropolitana Santiago, Chile
  • Fundacion Innovacion Cardiovascular /ID# 266742, Independencia, Santiago Metropolitan, Chile
  • Beijing Children's Hospital /ID# 266350, Beijing, Beijing Municipality, China
  • Children's Hospital Affiliated to Chongqing Medical University /ID# 266876, Yuzhong District, Chongqing Municipality, China
  • Xiamen Children's Hospital /ID# 266384, Xiamen, Fujian, China
  • Shenzhen Children's Hospital /ID# 266401, Shenzhen, Guangdong, China
  • Henan Children's Hospital Zhengzhou Children's Hospital /ID# 266832, Zhengzhou, Henan, China
  • Hunan Children's Hospital /ID# 266365, Changsha, Hunan, China
  • Dalian Women and Children's Medical Group /ID# 266675, Dalian, Liaoning, China
  • Chengdu Women and Children Center Hospital /ID# 266402, Chengdu, Sichuan, China
  • Kunming Childrens Hospital /ID# 266555, Kunming, Yunnan, China
  • The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU /ID# 266708, Wenzhou, Zhejiang, China
  • Klinika za dječje bolesti Zagreb /ID# 264936, Zagreb, City of Zagreb, Croatia
  • Poliklinika DermaPlus /ID# 265724, Zagreb, City of Zagreb, Croatia
  • Poliklinika Solmed /ID# 265070, Zagreb, City of Zagreb, Croatia
  • Specialty Hospital Medico /ID# 266116, Rijeka, Primorje-Gorski Kotar County, Croatia
  • Klinicki Bolnicki Centar KBC Split /ID# 265359, Split, Split-Dalmatia County, Croatia
  • CHU Toulouse - Hopital Larrey /ID# 255048, Toulouse, Haute-Garonne, France
  • Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois /ID# 265455, Vandœuvre-lès-Nancy, Meurthe-et-Moselle, France
  • CHU Bordeaux - Hopital Pellegrin /ID# 266818, Bordeaux, New Aquitaine, France
  • Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu /ID# 265449, Nantes, Pays de la Loire Region, France
  • Centre Hospitalier Universitaire de Clermont Ferrand - Hopital Estaing /ID# 267327, Clermont-Ferrand, Puy-de-Dome, France
  • CHU Amiens-Picardie Site Sud /ID# 255083, Amiens, Somme, France
  • AP-HP - Hopital Necker /ID# 255050, Paris, France
  • Centre Hospitalier d Argenteuil Victor Dupouy /ID# 265448, Argenteuil, Île-de-France Region, France
  • Universitaetsklinikum Erlangen /ID# 255168, Erlangen, Bavaria, Germany
  • Fachklinik Bad Bentheim /ID# 255165, Bad Bentheim, Lower Saxony, Germany
  • Universitaetsklinikum Muenster /ID# 255166, Münster, North Rhine-Westphalia, Germany
  • Universitaetsklinikum Carl Gustav Carus Dresden /ID# 255167, Dresden, Saxony, Germany
  • Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 267411, Berlin, Germany
  • DermaMed Research - Oroshaza /ID# 266995, Orosháza, Bekes County, Hungary
  • Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont /ID# 265653, Szeged, Csongrád megye, Hungary
  • Debreceni Egyetem-Klinikai Kozpont /ID# 265331, Debrecen, Hajdú-Bihar, Hungary
  • Schneider Childrens Medical Center of Israel /ID# 265617, Petah Tikva, Central District, Israel
  • HaEmek Medical Center /ID# 266416, Afula, Haifa District, Israel
  • Hadassah Medical Center-Hebrew University /ID# 255041, Jerusalem, Jerusalem, Israel
  • Soroka Medical Center /ID# 265251, Beersheba, Southern District, Israel
  • The Chaim Sheba Medical Center /ID# 265254, Ramat Gan, Tel Aviv, Israel
  • Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 267070, Rome, Roma, Italy
  • Ospedale Pediatrico Bambino Gesù /ID# 266118, Rome, Roma, Italy
  • IRCCS AOU di Bologna Policlinico Sant Orsola Malpighi /ID# 255118, Bologna, Italy
  • Eukarya PharmaSite /ID# 265274, Monterrey, Nuevo León, Mexico
  • Arke Smo Sa de Cv /Id# 266650, Veracruz, Mexico
  • Amsterdam UMC, locatie AMC /ID# 265406, Amsterdam, North Holland, Netherlands
  • Erasmus Medisch Centrum /ID# 265408, Rotterdam, South Holland, Netherlands
  • Specjalistyczny Niepubliczny Zaklad Opieki Zdrowotnej Alergologia Plus /ID# 265457, Poznan, Greater Poland Voivodeship, Poland
  • MICS Centrum Medyczne Torun /ID# 265454, Torun, Kuyavian-Pomeranian Voivodeship, Poland
  • Centrum Nowoczesnych Terapii Dobry Lekarz sp.z.o.o. /ID# 266030, Krakow, Lesser Poland Voivodeship, Poland
  • Klinika Osipowicz & Turkowski sp.z.o.o /ID# 267490, Warsaw, Masovian Voivodeship, Poland
  • Clinical Research Group Sp. z o.o. /ID# 266924, Warsaw, Masovian Voivodeship, Poland
  • Klinika Ambroziak Dermatologia /ID# 265458, Warsaw, Masovian Voivodeship, Poland
  • Royalderm Agnieszka Nawrocka /ID# 266606, Warsaw, Masovian Voivodeship, Poland
  • NZOZ Specjalistyczny Osrodek Dermatologiczny Dermal /ID# 266613, Bialystok, Podlaskie Voivodeship, Poland
  • Centrum Badan Klinicznych PI-House sp. z o.o. /ID# 265451, Gdansk, Pomeranian Voivodeship, Poland
  • Centrum Medyczne Angelius Provita /ID# 265456, Katowice, Silesian Voivodeship, Poland
  • Unidade Local de Saude de Coimbra, EPE /ID# 266115, Coimbra, Portugal
  • Unidade Local de Saude de Santo Antonio, E.P.E. /ID# 266112, Porto, Portugal
  • Unidade Local de Saude Sao Joao, EPE /ID# 266111, Porto, Portugal
  • Clinical Research Investigator Group, LLC /ID# 268366, Bayamón, Puerto Rico
  • Private Practice - Dr. Alma Cruz /ID# 264234, Carolina, Puerto Rico
  • National University Hospital /ID# 265685, Singapore, Singapore
  • KK Women's and Children's Hospital /ID# 266519, Singapore, Singapore
  • Narodny Ustav Detskych Chorob /ID# 265253, Bratislava, Bratislava Region, Slovakia
  • ALERSA, s.r.o. /ID# 266245, Košice, Košice Region, Slovakia
  • Univerzitna nemocnica L. Pasteura Kosice /ID# 265239, Košice, Košice Region, Slovakia
  • Fakultna nemocnica Trnava /ID# 265245, Trnava, Slovakia
  • Univerzitna nemocnica Martin /ID# 265947, Martin, Žilina Region, Slovakia
  • Korea University Ansan Hospital /ID# 264169, Ansan-si, Gyeonggido, South Korea
  • Soon Chun Hyang University Hospital Bucheon /ID# 264171, Bucheon-si, Gyeonggido, South Korea
  • Chungang University Hospital /ID# 266383, Dongjak-gu, Seoul Teugbyeolsi, South Korea
  • Seoul National University Hospital /ID# 264176, Seoul, Seoul Teugbyeolsi, South Korea
  • Konkuk University Medical Center /ID# 264178, Seoul, Seoul Teugbyeolsi, South Korea
  • Hallym University Kangnam Sacred Heart Hospital /ID# 267318, Seoul, Seoul Teugbyeolsi, South Korea
  • Hospital Sant Joan de Deu /ID# 255287, Esplugues de Llobregat, Barcelona, Spain
  • Hospital General Universitario Gregorio Maranon /ID# 255288, Madrid, Spain
  • Hospital Universitario La Paz /ID# 255286, Madrid, Spain
  • Consorci Hospital General Universitario de Valencia /ID# 255289, Valencia, Spain
  • Hospital Universitario Miguel Servet /ID# 255290, Zaragoza, Spain
  • Kaohsiung Chang Gung Memorial Hospital /ID# 267791, Kaohsiung City, Kaohsiung, Taiwan
  • New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical /ID# 266349, New Taipei City, Taiwan
  • National Taiwan University Hospital /ID# 265510, Taipei, Taiwan
  • Taipei Veterans General Hospital- Taipei City /ID# 265507, Taipei, Taiwan
  • Linkou Chang Gung Memorial Hospital - Taoyuan /ID# 263664, Taoyuan, Taiwan
  • Derriford Hospital and the Royal Eye Infirmary /ID# 266980, Plymouth, Devon, United Kingdom
  • St Thomas' Hospital - Guy's and St Thomas' NHS Foundation Trust /ID# 265237, London, Greater London, United Kingdom
  • Chelsea and Westminster Hospital /ID# 266389, London, Greater London, United Kingdom
  • St George University Hospitals NHS Foundation Trust /ID# 266984, London, Greater London, United Kingdom
  • University Hospital Southampton /ID# 266655, Southampton, Hampshire, United Kingdom
  • Queen Elizabeth University Hospital - NHS Greater Glasgow and Clyde /ID# 265219, Glasgow, Lanarkshire, United Kingdom
  • Manchester University NHS Foundation Trust /ID# 267693, Manchester, United Kingdom
  • Royal Victoria Infirmary /ID# 265238, Newcastle upon Tyne, United Kingdom
View source on ClinicalTrials.gov(opens in a new tab)Contact study team (email)