A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Israel

RecruitingPHASE3

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Conditions

Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma

Locations

USA Mitchell Cancer Institute ( Site 0014), Mobile, Alabama, United States
Banner MD Anderson Cancer Center ( Site 0059), Gilbert, Arizona, United States
Banner MD Anderson Cancer Center - University Medical Center Phoenix ( Site 0051), Phoenix, Arizona, United States
Arizona Oncology Associates - NAHOA ( Site 8007), Prescott, Arizona, United States
Alta Bates Summit Medical Center ( Site 0004), Berkeley, California, United States
Moores Cancer Center ( Site 0003), La Jolla, California, United States
Care Access - South Pasadena ( Site 0070), Pasadena, California, United States
Saint Joseph Hospital ( Site 0026), Denver, Colorado, United States
Lutheran Medical Center ( Site 0027), Golden, Colorado, United States
Intermountain Health St. Mary's Regional Hospital ( Site 0025), Grand Junction, Colorado, United States
Eastern CT Hematology & Oncology Associates ( Site 0033), Norwich, Connecticut, United States
Clermont Oncology Center ( Site 0046), Clermont, Florida, United States
Florida Cancer Specialists - South ( Site 7001), Fort Myers, Florida, United States
Florida Cancer Specialists - East ( Site 7002), West Palm Beach, Florida, United States
Parkview Research Center at Parkview Regional Medical Center ( Site 0002), Fort Wayne, Indiana, United States
University of Iowa Health Care. ( Site 0017), Waukee, Iowa, United States
University of Iowa Health Care. ( Site 0057), Waukee, Iowa, United States
Saint Elizabeth Healthcare ( Site 0041), Edgewood, Kentucky, United States
Corewell Health-Lemmon Holton Cancer Pavilion ( Site 0011), Grand Rapids, Michigan, United States
Regions Hospital ( Site 0042), Saint Louis Park, Minnesota, United States
MidAmerica Cancer Care, LLC ( Site 0043), Kansas City, Missouri, United States
Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana ( Site 0052), Billings, Montana, United States
Summit Medical Group Cancer Center ( Site 0007), Florham Park, New Jersey, United States
John Theurer Cancer Center at Hackensack University Medical Center ( Site 0016), Hackensack, New Jersey, United States
Roswell Park Cancer Institute ( Site 0023), Buffalo, New York, United States
Carolina Oncology Specialists, PA ( Site 0054), Charlotte, North Carolina, United States
Southeastern Medical Oncology Center ( Site 0049), Goldsboro, North Carolina, United States
Consultants in Medical Oncology and Hematology (CMOH) ( Site 8002), Broomall, Pennsylvania, United States
Cancer Care Associates Of York ( Site 0005), York, Pennsylvania, United States
Tennessee Oncology-Chattanooga ( Site 0045), Chattanooga, Tennessee, United States
Tennessee Oncology, PLLC - Elliston Place Plaza Medical Oncology & Hematology ( Site 0031), Nashville, Tennessee, United States
Texas Oncology - Central/South Texas ( Site 8008), Austin, Texas, United States
The Center for Cancer and Blood Disorders ( Site 0032), Fort Worth, Texas, United States
Texas Oncology - San Antonio ( Site 8006), San Antonio, Texas, United States
Texas Oncology - Northeast Texas ( Site 8012), Tyler, Texas, United States
University of Virginia Cancer Center ( Site 0040), Charlottesville, Virginia, United States
Inova Schar Cancer Institute ( Site 0015), Fairfax, Virginia, United States
Virginia Commonwealth University (VCU) Medical Center ( Site 0030), Richmond, Virginia, United States
Medical Oncology Associates, PS (dba Summit Cancer Centers) ( Site 0010), Spokane, Washington, United States
SSM Health Dean Medical Group - South Madison Campus Health Research/Circuit Clinical ( Site 0048), Madison, Wisconsin, United States
University Hospital and UW Health Clinics ( Site 0006), Madison, Wisconsin, United States
Royal North Shore Hospital ( Site 2806), St Leonards, New South Wales, Australia
AZ Sint-Maarten, Campus Leopoldstraat 2 ( Site 0205), Mechelen, Antwerpen, Belgium
UZ Leuven-Hematology ( Site 0200), Leuven, Vlaams-Brabant, Belgium
Hospital 9 De Julho ( Site 2206), São Paulo, São Paulo, Brazil
Instituto Nacional de Câncer - INCA ( Site 2201), Rio de Janeiro, Brazil
Hospital Paulistano-Americas Oncologia ( Site 2202), São Paulo, Brazil
BC Cancer Kelowna ( Site 0112), Kelowna, British Columbia, Canada
BC Cancer Victoria ( Site 0109), Victoria, British Columbia, Canada
William Osler Health System ( Site 0103), Brampton, Ontario, Canada
The Ottawa Hospital - General Campus ( Site 0102), Ottawa, Ontario, Canada
McGill University Health Centre ( Site 0106), Montreal, Quebec, Canada
Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski ( Site 0100), Rimouski, Quebec, Canada
FALP-UIDO ( Site 2300), Santiago, Region M. de Santiago, Chile
Clínica Alemana de Santiago-Unidad de Investigaciones ( Site 2306), Santiago, Region M. de Santiago, Chile
Bradfordhill-Clinical Area ( Site 2310), Santiago, Region M. de Santiago, Chile
Anhui Provincial Cancer Hospital ( Site 2001), Hefei, Anhui, China
Peking University First Hospital ( Site 2022), Beijing, Beijing Municipality, China
Peking University Third Hospital-Hematology ( Site 2011), Beijing, Beijing Municipality, China
Chongqing University Cancer Hospital ( Site 2041), Chongqing, Chongqing Municipality, China
Southern Medical University Nanfang Hospital-Department of Hematopathology ( Site 2006), Guangzhou, Guangdong, China
Sun Yat-sen University Cancer Center ( Site 2028), Guangzhou, Guangdong, China
Liuzhou People's Hospital ( Site 2029), Liuchow, Guangxi, China
Guangxi Medical University Affiliated Tumor Hospital ( Site 2004), Nanning, Guangxi, China
The Affiliated Hospital of Guizhou Medical University ( Site 2024), Guiyang, Guizhou, China
Hainan General Hospital ( Site 2018), Haikou, Hainan, China
Wuhan Union Hospital ( Site 2015), Wuhan, Hebei, China
Henan Cancer Hospital-hematology department ( Site 2025), Zhengzhou, Henan, China
Tongji Hospital Affiliated to Tongji Medical College of HUST ( Site 2016), Wuhan, Hubei, China
Hunan Cancer Hospital ( Site 2020), Changsha, Hunan, China
The Second Xiangya Hospital of Central South University ( Site 2010), Changsha, Hunan, China
Jiangsu Province Hospital ( Site 2000), Nanjing, Jiangsu, China
The First Affliated Hospital of Suzhou University ( Site 2027), Suzhou, Jiangsu, China
The Affiliated Hospital of Xuzhou Medical College ( Site 2013), Xuzhou, Jiangsu, China
The First Affiliated Hospital of Nanchang University ( Site 2023), Nanchang, Jiangxi, China
Jiangxi Provincial Cancer Hospital ( Site 2009), Nanchang, Jiangxi, China
The First Hospital of Jilin University-Hematology ( Site 2030), Changchun, Jilin, China
Shaanxi provincial people's hospital ( Site 2012), Xi'an, Shaanxi, China
Shandong Cancer Hospital ( Site 2003), Jinan, Shandong, China
Shanxi Cancer Hospital ( Site 2033), Taiyuan, Shanxi, China
West China Hospital, Sichuan University-Head and Neck Oncology ( Site 2026), Chengdu, Sichuan, China
Tianjin Medical University Cancer Institute & Hospital-lymphoma ( Site 2019), Tianjin, Tianjin Municipality, China
Institute of hematology&blood disease hospital-Lymphoma ( Site 2005), Tianjin, Tianjin Municipality, China
Xinjiang Medical University Cancer Hospital - Urumqi ( Site 2014), Ürümqi, Xinjiang, China
The first Affiliated Hospital, Zhejiang University School of Medicine-Hematology ( Site 2002), Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital ( Site 2017), Hangzhou, Zhejiang, China
Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 2405), Valledupar, Cesar Department, Colombia
IMAT S.A.S ( Site 2401), Montería, Departamento de Córdoba, Colombia
Fundacion Valle del Lili- CIC-Oncology CIC ( Site 2402), Cali, Valle del Cauca Department, Colombia
Fakultni nemocnice Hradec Kralove-IV. interni hematologicka klinika ( Site 0301), Hradec Králové, Czechia
Fakultni nemocnice Olomouc ( Site 0303), Olomouc, Czechia
Vseobecna fakultni nemocnice v Praze-I. Interní klinika - klinika hematologie ( Site 0302), Prague, Czechia
Aalborg Universitetshospital, Syd ( Site 0403), Aalborg, North Denmark, Denmark
Roskilde Sygehus-Department of Hematology ( Site 0402), Roskilde, Region Sjælland, Denmark
Odense Universitetshospital-Department of Hematology ( Site 0401), Odense C, Region Syddanmark, Denmark
Universitaetsklinikum Ulm. ( Site 0601), Ulm, Baden-Wurttemberg, Germany
VK&K Studien GbR ( Site 0607), Landshut, Bavaria, Germany
Kliniken Maria Hilf ( Site 0603), Mönchengladbach, North Rhine-Westphalia, Germany
InVO Institut für Versorgungsforschung in der Onkologie ( Site 0606), Koblenz, Rhineland-Palatinate, Germany
Universitätsklinikum Halle ( Site 0604), Halle, Saxony-Anhalt, Germany
Onkologische Schwerpunktpraxis Kurfuerstendamm ( Site 0600), Berlin, Germany
Evangelismos General Hospital of Athens ( Site 0700), Athens, Attica, Greece
General Hospital of Athens "Laiko" ( Site 0704), Athens, Attica, Greece
University Hospital of Alexandroupolis ( Site 0701), Alexandroupoli, East Macedonia and Thrace, Greece
University Hospital of Ioannina ( Site 0702), Ioannina, Greece
Queen Mary Hospital ( Site 3300), Hong Kong, Hong Kong
Rambam Health Care Campus-Hematology and Bone Marrow Transplantation ( Site 1503), Haifa, Israel
Bnai Zion Medical Center ( Site 1505), Haifa, Israel
Hadassah Medical Center-Hemato-Oncology ( Site 1500), Jerusalem, Israel
Galilee Medical Center ( Site 1507), Nahariya, Israel
Rabin Medical Center ( Site 1504), Petah Tikva, Israel
Sheba Medical Center-Hemato Oncology ( Site 1501), Ramat Gan, Israel
Yitzhak Shamir Medical Center. ( Site 1506), Ẕerifin, Israel
Nagoya University Hospital ( Site 1907), Nagoya, Aichi-ken, Japan
Gunma University Hospital ( Site 1903), Maebashi, Gunma, Japan
Hokkaido University Hospital ( Site 1900), Sapporo, Hokkaido, Japan
Kobe City Medical Center General Hospital ( Site 1910), Kobe, Hyōgo, Japan
Tohoku University Hospital ( Site 1901), Sendai, Miyagi, Japan
Kindai University Hospital ( Site 1909), Sakai, Osaka, Japan
Shimane University Hospital ( Site 1911), Izumo, Shimane, Japan
Cancer Institute Hospital of JFCR ( Site 1906), Koto, Tokyo, Japan
Chiba Cancer Center ( Site 1905), Chiba, Japan
Kyushu University Hospital ( Site 1914), Fukuoka, Japan
Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital ( Site 1913), Hiroshima, Japan
Okayama University Hospital ( Site 1912), Okayama, Japan
Japanese Red Cross Osaka Hospital ( Site 1908), Osaka, Japan
Yamagata University Hospital ( Site 1902), Yamagata, Japan
University Malaya Medical Centre ( Site 1604), Lembah Pantai, Kuala Lumpur, Malaysia
Hospital Pulau Pinang ( Site 1602), George Town, Pulau Pinang, Malaysia
Queen Elizabeth Hospital ( Site 1603), Kota Kinabalu, Sabah, Malaysia
Centro de Infusion Superare ( Site 2602), Mexico City, Mexico City, Mexico
Health Pharma Professional Research S.A. de C.V: ( Site 2608), Mexico City, Mexico City, Mexico
Grupo Médico ASSET ( Site 2611), Mexico City, Mexico
Waikato Hospital-Haematology ( Site 3202), Hamilton, Waikato Region, New Zealand
North Shore Hospital-Department of Haematology ( Site 3200), Auckland, New Zealand
Aotearoa Clinical Trials ( Site 3201), Auckland, New Zealand
Akershus Universitetssykehus ( Site 0902), Lørenskog, Akershus, Norway
Sykehuset i Vestfold ( Site 0903), Tønsberg, Vestfold, Norway
Oslo Universitetssykehus Rikshospitalet-Avdeling for blodsykdommer ( Site 0901), Oslo, Norway
Centro Medico Monte Carmelo-Oncology ( Site 2706), Arequipa, Ariqipa, Peru
Clínica Anglo Americana ( Site 2701), Lima, Peru
Pratia MCM Krakow ( Site 1007), Krakow, Lesser Poland Voivodeship, Poland
Uniwersytecki Szpital Kliniczny nr 1 w Lublinie-Oddział Hematoonkologii-Transplantacji Szpiku i Chem ( Site 1006), Lublin, Lublin Voivodeship, Poland
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Kilinka Onkologii I Hematologii ( Site 1004), Warsaw, Masovian Voivodeship, Poland
Uniwersyteckie Centrum Kliniczne-Klinika Hematologii i Transplantologii ( Site 1011), Gdansk, Pomeranian Voivodeship, Poland
Wojewódzki Szpital Specjalistyczny im. J. Korczaka w Słupsku-Oddział Hematologii i Transplantacji ( Site 1013), Słupsk, Pomeranian Voivodeship, Poland
Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 1000), Gliwice, Silesian Voivodeship, Poland
Pratia Onkologia Katowice ( Site 1009), Katowice, Silesian Voivodeship, Poland
Samodzielny Publiczny Zakład Opieki Zdrowotnej MSWiA w Olsztynie-Oddzial Kliniczny Hematologii ( Site 1005), Olsztyn, Warmian-Masurian Voivodeship, Poland
Instituto Português de Oncologia de Lisboa Francisco Gentil ( Site 3103), Lisbon, Lisbon District, Portugal
Champalimaud Foundation ( Site 3102), Lisbon, Lisbon District, Portugal
Unidade Local de Saude Gaia/Espinho - Hospital Eduardo Santos Silva ( Site 3107), Vila Nova de Gaia, Porto District, Portugal
Unidade Local de Saude Lisboa Ocidental - Hospital de São Francisco Xavier ( Site 3104), Lisbon, Portugal
Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 3106), Lisbon, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 3100), Porto, Portugal
Wits Clinical Research ( Site 1102), Johannesburg, Gauteng, South Africa
Netcare Pretoria East Hospital-Alberts Cellular Therapy ( Site 1101), Pretoria, Gauteng, South Africa
Groote Schuur Hospital-Clinical Haematology ( Site 1100), Cape Town, Western Cape, South Africa
Haemalife ( Site 1105), Kuilsriver, Western Cape, South Africa
Constantiaberg Haematology ( Site 1106), Plumstead, Western Cape, South Africa
Institut Català d'Oncologia - L'Hospitalet-Haematology Department ( Site 1207), L'Hospitalet Del Llobregat, Barcelona, Spain
HOSPITAL CLÍNIC DE BARCELONA ( Site 1202), Barcelona, Catalonia, Spain
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 1209), Pozuelo de Alarcón, Madrid, Spain
HOSPITAL UNIVERSITARIO PUERTA DE HIERRO MAJADAHONDA ( Site 1208), Majadahonda, Madrid, Comunidad de, Spain
hospital universitario de canarias ( Site 1205), San Cristóbal de La Laguna, Santa Cruz De Tenerife, Spain
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1206), Barcelona, Spain
Hospital Universitario de Salamanca - Complejo Asistencial U-Servicio de Hematologia ( Site 1201), Salamanca, Spain
Karolinska Universitetssjukhuset Solna ( Site 1302), Stockholm, Stockholm County, Sweden
Chang Gung Memorial Hospital at Kaohsiung-Division of Hematology and Oncology ( Site 1702), Kaohsiung City, Taiwan
National Cheng Kung University Hospital ( Site 1700), Tainan, Taiwan
National Taiwan University Hospital ( Site 1701), Taipei, Taiwan
Chang Gung Medical Foundation-Linkou Branch ( Site 1703), Taoyuan District, Taiwan
Faculty of Medicine Siriraj Hospital-Division of Hematology, Department of Medicine ( Site 1801), Bangkok, Bangkok, Thailand
Chulalongkorn University ( Site 1802), Pathumwan, Bangkok, Thailand
Naresuan University Hospital ( Site 1804), Muang, Changwat Phitsanulok, Thailand
Songklanagarind hospital ( Site 1803), Hat Yai, Changwat Songkhla, Thailand
Maharaj Nakorn Chiang Mai Hospital ( Site 1800), Muang, Chiang Mai, Thailand
Ankara Universitesi Tip Fakultesi Hastanesi-hematology ( Site 1401), Ankara, Turkey (Türkiye)
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1407), Ankara, Turkey (Türkiye)
Antalya Egitim ve Arastırma Hastanesi ( Site 1409), Antalya, Turkey (Türkiye)
Trakya University Medical Faculty Hospital-Hematology ( Site 1403), Edirne, Turkey (Türkiye)
Mega Medipol ( Site 1412), Istanbul, Turkey (Türkiye)
Sisli Florence Nightingale Hastanesi ( Site 1411), Istanbul, Turkey (Türkiye)
Marmara Universitesi Pendik Egitim Arastirma Hastanesi ( Site 1408), Istanbul, Turkey (Türkiye)
Ege Universitesi Hastanesi ( Site 1404), Izmir, Turkey (Türkiye)
Ondokuz Mays Üniversitesi ( Site 1410), Samsun, Turkey (Türkiye)
Southmead Hospital ( Site 3010), Bristol, Bristol, City of, United Kingdom
Royal Lancaster Infirmary ( Site 3012), Lancaster, Lancashire, United Kingdom
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 3006), London, London, City of, United Kingdom
The Churchill Hospital ( Site 3007), Oxford, Oxfordshire, United Kingdom
GenesisCare - Bristol ( Site 3011), Bristol, South Gloucestershire, United Kingdom
GenesisCare - Cambridge ( Site 3001), Newmarket, Suffolk, United Kingdom
GenesisCare - Windsor ( Site 3002), Windsor, Windsor And Maidenhead, United Kingdom
Barnet Hospital ( Site 3005), Barnet, United Kingdom
St James's University Hospital ( Site 3004), Leeds, United Kingdom
City Hospital, Nottingham University Hospitals NHS Trust ( Site 3003), Nottingham, United Kingdom

View source on ClinicalTrials.gov Contact study team (email)