A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

Israel

RecruitingPHASE3

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Conditions

Essential Thrombocythemia

Locations

Palo Verde Hematology/ Oncology Center, Ltd. ( Site 3496), Glendale, Arizona, United States
Los Angeles Cancer Network ( Site 3491), Glendale, California, United States
Stanford Cancer Institute ( Site 0107), Stanford, California, United States
The Lundquist Institute ( Site 3423), Torrance, California, United States
University of Colorado Anschutz Medical Campus ( Site 3425), Aurora, Colorado, United States
Tufts Medical Center ( Site 3408), Boston, Massachusetts, United States
University of Michigan ( Site 0008), Ann Arbor, Michigan, United States
Henry Ford Hospital ( Site 3413), Detroit, Michigan, United States
Optum Care Cancer Center ( Site 3497), Las Vegas, Nevada, United States
Roswell Park Cancer Institute ( Site 3421), Buffalo, New York, United States
Duke University Health System (DUHS) ( Site 0016), Durham, North Carolina, United States
Wake Forest Baptist Health-Internal Medicine, Section on Hematology & Oncology ( Site 3400), Winston-Salem, North Carolina, United States
Medical University of South Carolina-Hollings Cancer Center ( Site 3426), Charleston, South Carolina, United States
University of Virginia ( Site 3422), Charlottesville, Virginia, United States
VCU Health Adult Outpatient Pavillion ( Site 3416), Richmond, Virginia, United States
Hospital Universitario Austral ( Site 0104), Pilar, Buenos Aires, Argentina
Hospital Italiano de Buenos Aires ( Site 0105), ABB, Buenos Aires F.D., Argentina
C.I.C.E. 9 de Julio ( Site 1001), San Miguel de Tucumán, Tucumán Province, Argentina
Royal Prince Alfred Hospital ( Site 1100), Camperdown, New South Wales, Australia
Liverpool Hospital-Haematology ( Site 0501), Liverpool, New South Wales, Australia
Royal North Shore Hospital ( Site 0003), St Leonards, New South Wales, Australia
Calvary Mater Newcastle ( Site 0505), Waratah, New South Wales, Australia
Royal Adelaide Hospital-Haematology Clinical Trials Unit ( Site 0001), Adelaide, South Australia, Australia
Monash Health-Haematology Research ( Site 0006), Clayton, Victoria, Australia
Western Health-Sunshine & Footscray Hospitals-Cancer Services-Cancer Research ( Site 0502), Melbourne, Victoria, Australia
Royal Perth Hospital-Haematology ( Site 0504), Perth, Western Australia, Australia
ZAS Cadix ( Site 1200), Antwerp, Belgium
The Moncton Hospital-Oncology ( Site 1500), Moncton, New Brunswick, Canada
The First Afflilated Hospital of Bengbu Medical College ( Site 3509), Bengbu, Anhui, China
Anhui Provincial Hospital ( Site 3513), Hefei, Anhui, China
Peking University Third Hospital-Hematology ( Site 3502), Beijing, Beijing Municipality, China
Peking Union Medical College Hospital ( Site 3531), Beijing, Beijing Municipality, China
The Second Affiliated Hospital Of Fujian Medical University ( Site 3525), Quanzhou, Fujian, China
The First Affiliated hospital of Xiamen University ( Site 3515), Xiamen, Fujian, China
Sun Yat-sen Memorial Hospital of Sun Yat-sen University ( Site 3524), Guangzhou, Guangdong, China
Southern Medical University Nanfang Hospital-Department of Hematopathology ( Site 3511), Guangzhou, Guangdong, China
The First Hospital of Hebei Medical University ( Site 3510), Shijiazhuang, Hebei, China
Henan Cancer Hospital-hematology department ( Site 3504), Zhengzhou, Henan, China
Wuhan Union Hospital ( Site 3500), Wuhan, Hubei, China
Jiangsu Province Hospital ( Site 3507), Nanjing, Jiangsu, China
Affiliated Hospital of Nantong University ( Site 3527), Nantong, Jiangsu, China
The First affiliated hospital of Nanchang University (Xianghu campus) ( Site 3505), Nanchang, Jiangxi, China
The First Hospital of Jilin University-Hematology ( Site 3526), Changchun, Jilin, China
Shaanxi provincial people's hospital ( Site 3516), Xi'an, Shaanxi, China
Jinan Central Hospital ( Site 3523), Jinan, Shandong, China
Zhongshan Hospital,Fudan University-Hematology ( Site 3530), Shanghai, Shanghai Municipality, China
Huashan Hospital, Fudan University ( Site 3529), Shanghai, Shanghai Municipality, China
West China Hospital, Sichuan University ( Site 3518), Chengdu, Sichuan, China
Institute of hematology&blood disease hospital ( Site 3501), Tianjin, Tianjin Municipality, China
The first Affiliated Hospital, Zhejiang University School of Medicine ( Site 3508), Hangzhou, Zhejiang, China
Zhejiang University School of Medicine-The Fourth Affiliated Hospital ( Site 3517), Yiwu, Zhejiang, China
Fundacion Colombiana de Cancerología Clinica Vida ( Site 1403), Medellín, Antioquia, Colombia
Los Cobos Medical Center ( Site 1404), Bogotá, Bogota D.C., Colombia
IMAT S.A.S ( Site 1401), Montería, Departamento de Córdoba, Colombia
Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou ( Site 0417), Rennes, Brittany Region, France
Centre Hospitalier Régional Universitaire de Tours - Hôpital-Hématologie et Thérapie Cellulaire ( Site 0413), Tours, Indre-et-Loire, France
Centre Hospitalier Universitaire de Limoges - Hôpital Dupuyt-Hématologie Clinique et Thérapie Cellu ( Site 1701), Limoges, Limousin, France
Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois-HEMATOLOGY ( Site 0407), Vandœuvre-lès-Nancy, Lorraine, France
Centre Hospitalier de Roubaix ( Site 1703), Roubaix, Nord, France
centre hospitalier lyon sud ( Site 0406), Pierre-Bénite, Rhone, France
Hôpital Saint-Louis-Centre d'Investigations Cliniques ( Site 0405), Paris, France
Hôpital Saint Antoine-Service d'Hématologie et de Thérapie Cellulaire ( Site 1702), Paris, Île-de-France Region, France
Universitätsklinikum Aachen ( Site 1801), Aachen, North Rhine-Westphalia, Germany
Universitaetsklinikum Carl Gustav Carus Dresden-Medical Dept I - Medical Oncology ( Site 0402), Dresden, Saxony, Germany
Universitätsklinikum Halle ( Site 0401), Halle, Saxony-Anhalt, Germany
Queen Mary Hospital ( Site 1901), Hksar, Hong Kong
Petz Aladar Egyetemi Oktato Korhaz ( Site 2000), Győr, Győr-Moson-Sopron, Hungary
Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókór-Haematológia osztály ( Site 0706), Nyíregyháza, Szabolcs-Szatmár-Bereg, Hungary
Semmelweis Egyetem-Belgyógyászati és Hematológiai Klinika ( Site 0708), Budapest, Hungary
Debreceni Egyetem Klinikai Kozpont-Belgyógyászati Klinika (Haematologia) ( Site 0707), Debrecen, Hungary
Soroka Medical Center ( Site 2100), Beersheba, Israel
Rambam Health Care Campus ( Site 2102), Haifa, Israel
Carmel Hospital ( Site 0906), Haifa, Israel
Hadassah Medical Center ( Site 0904), Jerusalem, Israel
Rabin Medical Center ( Site 0905), Petah Tikva, Israel
Sheba Medical Center ( Site 2101), Ramat Gan, Israel
Sourasky Medical Center ( Site 0902), Tel Aviv, Israel
Yitzhak Shamir Medical Center. ( Site 0901), Ẕerifin, Israel
Azienda Ospedaliero Universitaria di Ferrara ( Site 0304), Cona, Ferrara, Italy
IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 0308), Meldola, Forli-Cesena, Italy
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico ( Site 2201), Milan, Lombardy, Italy
Azienda Ospedaliera Universitaria Careggi ( Site 0030), Florence, Tuscany, Italy
Azienda Ospedaliero Universitaria Pisana-UO Ematologia UNIV ( Site 0309), Pisa, Tuscany, Italy
Istituto Oncologico Veneto IRCCS-Oncoematologia ( Site 0306), Castelfranco Veneto, Veneto, Italy
Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo ( Site 0034), Alessandria, Italy
Azienda Ospedaliero Universitaria delle Marche ( Site 0302), Ancona, Italy
Arcispedale Santa Maria Nuova ( Site 0301), Reggio Emilia, Italy
Ospedale Mauriziano ( Site 0305), Torino, Italy
Ospedale di Circolo e Fondazione Macchi Varese ( Site 2200), Varese, Italy
Fujita Health University Hospital ( Site 3613), Toyoake, Aichi-ken, Japan
National Cancer Center Hospital East ( Site 3610), Kashiwa, Chiba, Japan
Ehime University Hospital ( Site 3612), Tōon, Ehime, Japan
Hokkaido University Hospital ( Site 3601), Sapporo, Hokkaido, Japan
Kobe City Medical Center General Hospital ( Site 3603), Kobe, Hyōgo, Japan
Kanazawa University Hospital ( Site 3614), Kanazawa, Ishikawa-ken, Japan
Mie University Hospital ( Site 3615), Tsu, Mie-ken, Japan
National Hospital Organization Sendai Medical Center ( Site 3617), Sendai, Miyagi, Japan
Kansai Medical University Hospital ( Site 3607), Hirakata, Osaka, Japan
Kindai University Hospital ( Site 3600), Sakai, Osaka, Japan
Juntendo University Hospital ( Site 3611), Bunkyo-ku, Tokyo, Japan
Nippon Medical School Hospital ( Site 3608), Bunkyo-ku, Tokyo, Japan
University of Yamanashi Hospital ( Site 3606), Chūō, Yamanashi, Japan
Kyushu University Hospital ( Site 3605), Fukuoka, Japan
Fukushima Medical University Hospital ( Site 3616), Fukushima, Japan
University of Miyazaki Hospital ( Site 3609), Miyazaki, Japan
Okayama University Hospital ( Site 3604), Okayama, Japan
Spaarne Gasthuis - Hoofddorp-Oncology ( Site 2301), Hoofddorp, North Holland, Netherlands
Albert Schweitzer Ziekenhuis, locatie Dordwijk-Internal Medicine ( Site 2302), Dordrecht, South Holland, Netherlands
University Medical Center Groningen ( Site 2304), Groningen, Netherlands
Martini Ziekenhuis ( Site 2300), Groningen, Netherlands
North Shore Hospital-Department of Haematology ( Site 0051), Auckland, New Zealand
Aotearoa Clinical Trials ( Site 0050), Auckland, New Zealand
Pratia Onkologia Katowice ( Site 0702), Katowice, Silesian Voivodeship, Poland
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Hematologii i Transplantacji S ( Site 2504), Kielce, Świętokrzyskie Voivodeship, Poland
Unidade Local de Saude de Braga - Hospital de Braga ( Site 0415), Braga, Portugal
Unidade Local de Saude Lisboa Ocidental - Hospital de São Francisco Xavier ( Site 2600), Lisbon, Portugal
Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 0414), Porto, Portugal
Seoul National University Bundang Hospital-Hematology ( Site 0605), Seongnam, Kyonggi-do, South Korea
Korea University Anam Hospital ( Site 0604), Seoul, South Korea
Asan Medical Center ( Site 0603), Seoul, South Korea
The Catholic Univ. of Korea Seoul St. Mary's Hospital ( Site 0606), Seoul, South Korea
Hospital Germans Trias i Pujol-Instituto Catalán de Oncología de Badalona ( Site 0409), Badalona, Barcelona, Spain
Institut Català d'Oncologia - L'Hospitalet-Haematology Department ( Site 2801), L'Hospitalet Del Llobregat, Barcelona, Spain
Hospital del Mar ( Site 2807), Barcelona, Catalonia, Spain
HOSPITAL CLÍNIC DE BARCELONA ( Site 2800), Barcelona, Catalonia, Spain
CHUS - Hospital Clinico Universitario ( Site 0421), Santiago de Compostela, La Coruna, Spain
Hospital Universitario Ramón y Cajal-Hematology ( Site 2803), Madrid, Madrid, Comunidad de, Spain
Hospital Costa del Sol-Hematology Service ( Site 0412), Marbella, Malaga, Spain
Hospital General Universitario de Albacete ( Site 0408), Albacete, Spain
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 0404), Barcelona, Spain
Hospital Universitario 12 de Octubre ( Site 2806), Madrid, Spain
Hospital Universitario Virgen de la Victoria ( Site 0418), Málaga, Spain
Hospital Universitario de Salamanca - Complejo Asistencial U-Servicio de Hematologia ( Site 0419), Salamanca, Spain
Hospital Universitario Doctor Peset ( Site 0411), Valencia, Spain
Karolinska Universitetssjukhuset Huddinge ( Site 2900), Huddinge, Stockholm County, Sweden
Universitetssjukhuset Örebro ( Site 0403), Örebro, Örebro County, Sweden
Chang Gung Memorial Hospital- Chiayi ( Site 3102), Chiayi City, Chiayi, Taiwan
Chang Gung Memorial Hospital at Kaohsiung-Division of Hematology and Oncology ( Site 3104), Kaohsiung City, Taiwan
National Cheng Kung University Hospital-Clinical Trial Center ( Site 3105), Tainan, Taiwan
National Taiwan University Hospital ( Site 3101), Taipei, Taiwan
Chang Gung Medical Foundation-Linkou Branch ( Site 3103), Taoyuan District, Taiwan
Ege Universitesi Hastanesi ( Site 3202), Bornova, İzmir, Turkey (Türkiye)
Hacettepe Universite Hastaneleri-Department of Hematology ( Site 3204), Ankara, Turkey (Türkiye)
Ankara UTF Cebeci Arastırma ve Uygulama Hastanesi ( Site 3210), Ankara, Turkey (Türkiye)
Ankara Bilkent Şehir Hastanesi ( Site 3201), Ankara, Turkey (Türkiye)
Antalya Egitim ve Arastırma Hastanesi ( Site 3207), Antalya, Turkey (Türkiye)
Trakya University Medical Faculty Hospital-Hematology ( Site 3200), Edirne, Turkey (Türkiye)
Medipol Mega Universite Hastanesi-oncology ( Site 3203), Istanbul, Turkey (Türkiye)
Kocaeli Üniversitesi-Hematology ( Site 3205), Kocaeli, Turkey (Türkiye)
VM Medical Park Mersin Hastanesi ( Site 3208), Mersin, Turkey (Türkiye)
Ondokuz Mayıs Universitesi-hematology ( Site 3206), Samsun, Turkey (Türkiye)
Addenbrooke's Hospital ( Site 3303), Cambridge, Cambridgeshire, United Kingdom
Gloucestershire Royal Hospital ( Site 3302), Gloucester, Gloucestershire, United Kingdom
Lincoln County Hospital ( Site 3310), Lincoln, Great Britain, United Kingdom
Boston Pilgrim Hospital ( Site 3301), Boston, Lincolnshire, United Kingdom
University College London Hospital ( Site 3300), London, London, City of, United Kingdom
Guy's & St Thomas' NHS Foundation Trust ( Site 3305), London, London, City of, United Kingdom
King's College Hospital ( Site 3308), London, London, City of, United Kingdom
Royal Gwent Hospital ( Site 3304), Gwent, Newport, United Kingdom
GenesisCare - Windsor ( Site 3309), Windsor, Windsor And Maidenhead, United Kingdom
The Christie NHS Foundation Trust ( Site 3307), Manchester, United Kingdom

View source on ClinicalTrials.gov Contact study team (email)