Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

Israel

RecruitingPHASE3

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Conditions

Non-small Cell Lung Cancer (NSCLC)

Locations

UCLA Hematology/Oncology - Santa Monica ( Site 0023), Los Angeles, California, United States
Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0001), Jacksonville, Florida, United States
Mid Florida Hematology and Oncology Center ( Site 0005), Orange City, Florida, United States
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 0003), Marietta, Georgia, United States
Karmanos Cancer Institute ( Site 0018), Detroit, Michigan, United States
Mayo Clinic in Rochester, Minnesota-Mayo Clinic Comprehensive Cancer Center ( Site 0027), Rochester, Minnesota, United States
Hattiesburg Clinic Hematology/Oncology ( Site 0010), Hattiesburg, Mississippi, United States
University Of Nebraska Medical Center ( Site 0011), Omaha, Nebraska, United States
Englewood Hospital and Medical Center ( Site 0033), Englewood, New Jersey, United States
Atlantic Health System Morristown Medical Center ( Site 0031), Morristown, New Jersey, United States
Capital Health Medical Center - Hopewell ( Site 0006), Pennington, New Jersey, United States
University of Cincinnati Medical Center-University of Cincinnati Cancer Center ( Site 0015), Cincinnati, Ohio, United States
Tennessee Oncology (0036), Nashville, Tennessee, United States
University of Texas MD Anderson (0037), Houston, Texas, United States
VCU Health Adult Outpatient Pavillion ( Site 0026), Richmond, Virginia, United States
St. George Private Hospital ( Site 3004), Kogarah, New South Wales, Australia
Westmead Hospital ( Site 3000), Westmead, New South Wales, Australia
Monash Health-Oncology Research ( Site 3001), Clayton, Victoria, Australia
Western Health-Sunshine & Footscray Hospitals-Cancer Services-Cancer Research ( Site 3003), Melbourne, Victoria, Australia
Liga Norte Riograndense Contra o Câncer-Centro de Pesquisa Clínica ( Site 0447), Natal, Rio Grande do Norte, Brazil
Hospital Nossa Senhora da Conceição-Centro Integrado de Pesquisa em Oncologia ( Site 0440), Porto Alegre, Rio Grande do Sul, Brazil
Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0444), Barretos, São Paulo, Brazil
Hospital Paulistano-Americas Oncologia ( Site 0441), São Paulo, Brazil
A. C. Camargo Cancer Center-CAPEC ( Site 0442), São Paulo, Brazil
Núcleo de Pesquisa Clínica da Rede São Camilo ( Site 0446), São Paulo, Brazil
William Osler Health System ( Site 0205), Brampton, Ontario, Canada
Princess Margaret Cancer Centre ( Site 0204), Toronto, Ontario, Canada
Centro Investigacion Cancer James Lind ( Site 0513), Temuco, Araucania, Chile
Clinica Universidad Catolica del Maule-Oncology ( Site 0501), Talca, Maule Region, Chile
Centro de Estudios Clínicos SAGA ( Site 0517), Santiago, Region M. de Santiago, Chile
Orlandi Oncologia-Oncology ( Site 0504), Santiago, Region M. de Santiago, Chile
FALP-UIDO ( Site 0509), Santiago, Region M. de Santiago, Chile
K2 Oncology ( Site 0514), Santiago, Region M. de Santiago, Chile
Clínica RedSalud Vitacura ( Site 0511), Santiago, Region M. de Santiago, Chile
Pontificia Universidad Catolica de Chile ( Site 0502), Santiago, Region M. de Santiago, Chile
Bradfordhill-Clinical Area ( Site 0507), Santiago, Region M. de Santiago, Chile
ONCOCENTRO APYS-ACEREY ( Site 0500), Viña del Mar, Valparaiso, Chile
Anhui Provincial Cancer Hospital ( Site 2830), Hefei, Anhui, China
Beijing Cancer hospital-Thoracic Cancer Department A ( Site 2810), Beijing, Beijing Municipality, China
Beijing Peking Union Medical College Hospital-pneumology department ( Site 2815), Beijing, Beijing Municipality, China
Chongqing University Cancer Hospital-Medical Oncology ( Site 2814), Chongqing, Chongqing Municipality, China
Fujian Cancer Hospital ( Site 2819), Fuzhou, Fujian, China
The First Affiliated hospital of Xiamen University ( Site 2820), Xiamen, Fujian, China
Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 2818), Guangzhou, Guangdong, China
Guangxi Medical University Cancer Hospital-Respiratory Oncology ( Site 2816), Nanning, Guangxi, China
Harbin Medical University Cancer Hospital-oncology of department ( Site 2807), Harbin, Heilongjiang, China
Henan Cancer Hospital-henan cancer hospital ( Site 2813), Zhengzhou, Henan, China
Tongji Hospital Tongji Medical,Science & Technology ( Site 2805), Wuhan, Hubei, China
Wuhan Union Hospital Cancer Center-Cancer Center ( Site 2806), Wuhan, Hubei, China
Hubei Cancer Hospital ( Site 2809), Wuhan, Hubei, China
The Second Xiangya Hospital of Central South University ( Site 2827), Changsha, Hunan, China
Hunan Cancer Hospital-thoracic oncology II ( Site 2808), Changsha, Hunan, China
Nanjing Drum Tower Hospital ( Site 2812), Nangjing, Jiangsu, China
The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2821), Nanchang, Jiangxi, China
Jilin Province Tumor Hospital-clinical research ( Site 2803), Changchun, Jilin, China
The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 2817), Xi'an, Shaanxi, China
Jinan Central Hospital-oncology department ( Site 2802), Jinan, Shandong, China
LinYi Cancer Hospital ( Site 2804), Linyi, Shandong, China
Shanghai Chest Hospital-Oncology department ( Site 2800), Shanghai, Shanghai Municipality, China
Fudan University Shanghai Cancer Center-Oncology ( Site 2811), Shanghai, Shanghai Municipality, China
West China Hospital, Sichuan University-Lung cancer center ( Site 2826), Chengdu, Sichuan, China
Sichuan Cancer hospital. ( Site 2822), Chengdu, Sichuan, China
Yunnan Province Cancer Hospital ( Site 2824), Kunming, Yunnan, China
Sir Run Run Shaw Hospital School of Medicine Zhejiang University ( Site 2828), Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital ( Site 2829), Hangzhou, Zhejiang, China
Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 1100), Brno, Brno-mesto, Czechia
Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni odd ( Site 1103), Ostrava, Ostrava Mesto, Czechia
Fakultni nemocnice Plzen ( Site 1104), Pilsen, Plzeň Region, Czechia
Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 1102), Olomouc, Czechia
Vseobecna fakultni nemocnice v Praze-Onkologicka klinika ( Site 1105), Prague, Czechia
Institut Bergonié - Centre Régional de Lutte Contre Le Cance-Medical Oncology ( Site 1303), Bordeaux, Aquitaine, France
CENTRE LEON BERARD ( Site 1305), Lyon Cedex08, Auvergne-Rhône-Alpes, France
CHU Charles Nicolle-pneumology, intensive care and thoracic oncology ( Site 1300), Rouen, Haute-Normandie, France
Groupe hospitalier Paris saint Joseph. ( Site 1307), Paris, France
Institut Curie-Thorax Institute ( Site 1304), Paris, France
Universitaetsklinikum Freiburg ( Site 1405), Freiburg, Brandenburg, Germany
Universitätsmedizin Göttingen - Georg-August-Universität-Klinik für Hämatologie und Medizinische On ( Site 1407), Göttingen, Lower Saxony, Germany
Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung ( Site 1400), Essen, North Rhine-Westphalia, Germany
Klinikum Chemnitz - Flemmingstraße ( Site 1401), Chemnitz, Saxony, Germany
Universitaetsklinikum Carl Gustav Carus Dresden ( Site 1402), Dresden, Saxony, Germany
Asklepios Klinik Harburg ( Site 1403), Hamburg, Germany
Errikos Dunant Hospital Center-Fourth Department of Oncology and Clinical Trials Unit ( Site 2705), Athens, Attica, Greece
THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol ( Site 2700), Athens, Attica, Greece
Aretaieio Hospital ( Site 2702), Athens, Attica, Greece
ATTIKON GENERAL UNIVERSITY HOSPITAL-Oncology ( Site 2704), Chaidari, Athens, Attica, Greece
"Theagenio" Cancer Hospital of Thessaloniki ( Site 2703), Thessaloniki, Central Macedonia, Greece
Papageorgiou General Hospital of Thessaloniki ( Site 2701), Thessaloniki, Greece
Hong Kong Integrated Oncology Centre ( Site 3200), Central, Hong Kong
Queen Mary Hospital ( Site 3203), Hksar, Hong Kong
Queen Elizabeth Hospital-Department of Clinical Oncology ( Site 3204), Kowloon, Hong Kong
Princess Margaret Hospital-Department of Oncology ( Site 3201), Lai Chi Kok, Hong Kong
Rambam Health Care Campus-Oncology Division ( Site 1702), Haifa, Israel
Shaare Zedek Medical Center ( Site 1700), Jerusalem, Israel
Rabin Medical Center ( Site 1703), Petah Tikva, Israel
IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"-Oncologia Medica ( Site 1806), Meldola, Emilia-Romagna, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Medical Oncology ( Site 1802), Rome, Lazio, Italy
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1800), Milan, Lombardy, Italy
Istituto Clinico Humanitas ( Site 1803), Rozzano, Lombardy, Italy
Istituto Nazionale Tumori Regina Elena-Oncologia Medica 2 ( Site 1805), Rome, Roma, Italy
Aichi Cancer Center ( Site 3400), Nagoya, Aichi-ken, Japan
Fujita Health University Hospital ( Site 3419), Toyoake, Aichi-ken, Japan
National Cancer Center Hospital East ( Site 3406), Kashiwa, Chiba, Japan
National Hospital Organization Shikoku Cancer Center ( Site 3415), Matsuyama, Ehime, Japan
Gunma Prefectural Cancer Center ( Site 3418), Otashi, Gunma, Japan
Takarazuka City Hospital ( Site 3409), Takarazuka, Hyōgo, Japan
Kanazawa University Hospital ( Site 3414), Kanazawa, Ishikawa-ken, Japan
Kanagawa Cancer Center ( Site 3404), Yokohama, Kanagawa, Japan
Miyagi Cancer Center ( Site 3416), Natori-shi, Miyagi, Japan
Sendai Kousei Hospital ( Site 3401), Sendai, Miyagi, Japan
Niigata Cancer Center Hospital ( Site 3405), Niigata, Niigata, Japan
Kansai Medical University Hospital ( Site 3410), Hirakata, Osaka, Japan
Shizuoka Cancer Center ( Site 3403), Nagaizumi-cho,Sunto-gun, Shizuoka, Japan
Cancer Institute Hospital of JFCR ( Site 3402), Koto, Tokyo, Japan
Chiba University Hospital ( Site 3411), Chiba, Japan
National Hospital Organization Kyushu Medical Center ( Site 3412), Fukuoka, Japan
Kyushu University Hospital ( Site 3407), Fukuoka, Japan
Okayama University Hospital ( Site 3417), Okayama, Japan
Osaka International Cancer Institute ( Site 3413), Osaka, Japan
Nippon Medical School Hospital ( Site 3408), Tokyo, Japan
Hospital Raja Perempuan Zainab II-Medical Department ( Site 3502), Kota Bharu, Kelantan, Malaysia
National Cancer Institute-Radiotherapy and Oncology ( Site 3504), Putrajaya, Kuala Lumpur, Malaysia
Sarawak General Hospital-Radiotherapy Unit ( Site 3500), Kuching, Sarawak, Malaysia
CIO - Centro de Inmuno-Oncología de Occidente ( Site 0706), Guadalajara, Jalisco, Mexico
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Hematologia and Oncologia ( Site 0704), Monterrey, Nuevo León, Mexico
Centro de Investigacion Clinica de Oaxaca ( Site 0701), Oaxaca City, Oaxaca, Mexico
Clinica Integral Internacional de Oncología ( Site 0705), Puebla City, Mexico
THE MEDICAL CITY ILOILO-The Medical City Iloilo - Clinical and Translational Research Institute-Ilo ( Site 3600), Iloilo City, Iloilo, Philippines
Manila Doctors Hospital-Clinical Trial Office ( Site 3604), Manila, National Capital Region, Philippines
Asian Hospital and Medical Center ( Site 3605), Muntinlupa, National Capital Region, Philippines
THE MEDICAL CITY-Cancer Research Center ( Site 3603), Pasig, National Capital Region, Philippines
ST. LUKE'S MEDICAL CENTER ( Site 3601), Quezon City, National Capital Region, Philippines
CARDINAL SANTOS MEDICAL CENTER-Research Room ( Site 3602), San Juan City, Metro Manila, National Capital Region, Philippines
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2003), Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland
Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu ( Site 2009), Torun, Kuyavian-Pomeranian Voivodeship, Poland
Instytut Gruźlicy i Chorób Płuc w Warszawie ( Site 2011), Warsaw, Masovian Voivodeship, Poland
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 2000), Warsaw, Masovian Voivodeship, Poland
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 2001), Przemyśl, Podkarpackie Voivodeship, Poland
Narodowy Instytut Onkologii - Oddzial w Gliwicach-II Klinika Radioterapi i Chemioterapii ( Site 2002), Gliwice, Silesian Voivodeship, Poland
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zaklad Opieki Zdrowotnej ( Site 2005), Kielce, Świętokrzyskie Voivodeship, Poland
Chonnam National University Hwasun Hospital-Pulmonology ( Site 3807), Hwasun, Jeonranamdo, South Korea
National Cancer Center-Lung Cancer Center ( Site 3810), Goyang-si, Kyonggi-do, South Korea
Seoul National University Bundang Hospital ( Site 3806), Seongnam, Kyonggi-do, South Korea
The Catholic University Of Korea St. Vincent's Hospital-Medical Oncology ( Site 3803), Suwon, Kyonggi-do, South Korea
Pusan National University Yangsan Hospital-Lung Cancer Clinic ( Site 3811), Yangsan, Kyongsangnam-do, South Korea
Chungbuk National University Hospital-Internal medicine ( Site 3809), Cheongju-si, North Chungcheong, South Korea
Pusan National University Hospital ( Site 3805), Busan, Pusan-Kwangyokshi, South Korea
Chungnam national university hospital ( Site 3808), Junggu, Taejon-Kwangyokshi, South Korea
Kangbuk Samsung Hospital ( Site 3813), Seoul, South Korea
Severance Hospital, Yonsei University Health System-Lung Cancer Center ( Site 3804), Seoul, South Korea
Konkuk University Medical Center ( Site 3812), Seoul, South Korea
Asan Medical Center ( Site 3801), Seoul, South Korea
Samsung Medical Center-Division of Hematology/Oncology ( Site 3802), Seoul, South Korea
Korea University Guro Hospital-Internal Medicine ( Site 3800), Seoul, South Korea
HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Site 2304), Barcelona, Catalonia, Spain
Hospital Insular de Gran Canaria-Oncology ( Site 2305), Las Palmas de Gran Canaria, Las Palmas, Spain
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 2301), Pozuelo de Alarcón, Madrid, Spain
HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 2303), Madrid, Madrid, Comunidad de, Spain
H.R.U Málaga - Hospital General-Oncology ( Site 2302), Málaga, Malaga, Spain
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 2300), Barcelona, Spain
Clinica Universidad de Navarra-Medical Oncology ( Site 2306), Madrid, Spain
Chi Mei Medical Center ( Site 3910), Tainan, Tainan, Taiwan
National Taiwan University Cancer Center (NTUCC) ( Site 3903), Taipei City, Taipei, Taiwan
Changhua Christian Hospital ( Site 3908), Changhua, Taiwan
National Taiwan University Hospital - Hsinchu branch ( Site 3907), Hsinchu, Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 3912), Kaohsiung City, Taiwan
E-Da hospital ( Site 3911), Kaohsiung City, Taiwan
Chang Gung Memorial Hospital at Kaohsiung ( Site 3906), Kaohsiung City, Taiwan
National Cheng Kung University Hospital ( Site 3909), Tainan, Taiwan
National Taiwan University Hospital-Oncology ( Site 3904), Taipei, Taiwan
Mackay Memorial Hospital-Chest Medicine ( Site 3902), Taipei, Taiwan
Taipei Medical University Hospital ( Site 3900), Taipei, Taiwan
Faculty of Medicine Siriraj Hospital ( Site 4000), Bangkok, Bangkok, Thailand
Lampang Cancer Hospital ( Site 4005), Muang, Changwat Lampang, Thailand
Songklanagarind hospital ( Site 4001), Hat Yai, Changwat Songkhla, Thailand
Maharaj Nakorn Chiang Mai Hospital ( Site 4003), Muang, Chiang Mai, Thailand
Faculty of Medicine - Khon Kaen University ( Site 4004), Khon Kaen, Thailand
Sunpasitthiprasong Hospital-Oncology ( Site 4002), Ubon Ratchathani, Thailand
Medipol Mega Universite Hastanesi-oncology ( Site 2505), Stanbul, Istanbul, Turkey (Türkiye)
Ege Universitesi Hastanesi-Chest Diseases Department ( Site 2504), Bornova, İzmir, Turkey (Türkiye)
Adana Medical Park Seyhan Hastanesi ( Site 2506), Adana, Turkey (Türkiye)
Hacettepe Universite Hastaneleri-oncology hospital ( Site 2500), Ankara, Turkey (Türkiye)
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 2501), Ankara, Turkey (Türkiye)
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2502), Istanbul, Turkey (Türkiye)
ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 2606), London, Kensington and Chelsea, United Kingdom
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 2600), London, London, City of, United Kingdom
Guy's & St Thomas' NHS Foundation Trust-Oncology & Haematology Clinical Trials ( Site 2603), London, London, City of, United Kingdom
Royal Marsden Hospital (Sutton) ( Site 2605), Sutton, Surrey, United Kingdom
The Christie NHS Foundation Trust ( Site 2604), Manchester, United Kingdom
The Clatterbridge Cancer Centre ( Site 2602), Metropolitan Borough of Wirral, United Kingdom
Hanoi Oncology Hospital ( Site 4102), Hanoi, Hanoi, Vietnam
K Hospital - National Cancer Hospital ( Site 4105), Hanoi, Hanoi, Vietnam
National Lung Hospital-Oncology Department ( Site 4104), Hanoi, Hanoi, Vietnam

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