Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

City of Hope National Medical Center, Duarte, California, United States

University of California Irvine, Orange, California, United States

University of California San Francisco, San Francisco, California, United States

Adventist Health System/Sunbelt, Inc d/b/a AdventHealth Orlando, Orlando, Florida, United States

Cleveland Clinic Foundation, Cleveland, Ohio, United States

Saint Francis Hospital, Inc, Greenville, South Carolina, United States

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Canberra Hospital, Garran, Australian Capital Territory, Australia

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

Liverpool Hospital, Liverpool, New South Wales, Australia

Royal North Shore Hospital, St Leonards, New South Wales, Australia

Westmead Hospital, Westmead, New South Wales, Australia

Royal Brisbane and Womens Hospital, Herston, Queensland, Australia

Princess Alexandra Hospital, Woolloongabba, Queensland, Australia

Royal Adelaide Hospital, Adelaide, South Australia, Australia

Monash Medical Centre, Clayton, Victoria, Australia

Austin Health, Austin Hospital, Heidelberg, Victoria, Australia

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

The Alfred Hospital, Melbourne, Victoria, Australia

Fiona Stanley Hospital, Murdoch, Western Australia, Australia

Medizinische Universitaet Graz, Graz, Austria

Medizinische Universitaet Innsbruck, Innsbruck, Austria

Ordensklinikum Linz Elisabethinen, Linz, Austria

Hanusch Krankenhaus, Vienna, Austria

Institut Jules Bordet, Anderlecht, Belgium

AZ Sint-Jan Brugge-Oostende AV, Bruges, Belgium

Universite Catholique de Louvain Cliniques Universitaires Saint Luc, Brussels, Belgium

Universitair Ziekenhuis Antwerpen, Edegem, Belgium

Universitair Ziekenhuis Gent, Ghent, Belgium

Jessa Ziekenhuis - Campus Virga Jesse, Hasselt, Belgium

Centre Hospitalier Universitaire de Liege - Sart Tilman, Liège, Belgium

AZ Delta Campus Rumbeke, Roeselare, Belgium

Centre Hospitalier Universitaire-Universite Catholique de Louvain Namur-Site Godinne, Yvoir, Belgium

Igesd Instituto de Gestao Estrategica da Saude do Distrito Federal, Brasília, Federal District, Brazil

Hospital das Clinicas da Universidade Federal de Goias, Goiânia, Goiás, Brazil

Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

Fundacao Amaral Carvalho, Jaú, São Paulo, Brazil

Hosp Clin Fac Med Ribeirao Preto Usp, Ribeirão Preto, São Paulo, Brazil

Hospital de Base de Sao Jose do Rio Preto, São Jose Do Rio Preto, São Paulo, Brazil

Hemorio, Rio de Janeiro, Brazil

Instituto Cancer Sao Paulo Icesp, São Paulo, Brazil

University Multiprofile Hospital for Active Treatment Sveti Georgi EAD, Plovdiv, Bulgaria

Specialized Hospital for Active Treatment of Hematology Diseases EAD, Sofia, Bulgaria

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta, Canada

Vancouver General Hospital, Gordon and Leslie Diamond Health Care Centre, Vancouver, British Columbia, Canada

Cancer Care Manitoba, Winnipeg, Manitoba, Canada

Queen Elizabeth II, Health Sciences Centre, Halifax, Nova Scotia, Canada

Hamilton Health Sciences - Juravinski Hospital and Cancer Centre, Hamilton, Ontario, Canada

The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada

Princess Margaret Cancer Centre, Toronto, Ontario, Canada

CEMTL Hopital Maisonneuve Rosemont, Montreal, Quebec, Canada

Fundacion Arturo Lopez Perez, Santiago, Chile

Inmunocel, Santiago, Chile

Clinica Alemana de Santiago, Santiago, Chile

Fakultni nemocnice Brno, Brno, Czechia

Fakultni nemocnice Hradec Kralove, Hradec Králové, Czechia

Ustav hematologie a krevni transfuze, Prague, Czechia

Aalborg Universitetshospital, Aalborg, Denmark

Aarhus Universitetshospital, Aarhus N, Denmark

Rigshospitalet, København Ø, Denmark

Odense Universitetshospital, Odense, Denmark

North Estonia Medical Centre, Tallinn, Estonia

Tartu University Hospital, Tartu, Estonia

Helsinki University Hospital, Helsinki, Finland

Turku University Hospital, Turku, Finland

Hopital Henri Mondor, Créteil, France

Centre Hospitalier Universitaire de Dijon - Hopital du Bocage, Dijon, France

Centre Hospitalier de Versailles - Hopital Andre Mignot, Le Chesnay, France

Centre Hospitalier Regional Universitaire de Lille - Hopital Claude Huriez, Lille, France

Institut Paoli Calmettes, Marseille, France

Centre Hospitalier Universitaire de Nantes - Hopital Hotel Dieu, Nantes, France

Centre Hospitalier Universitaire Archet 2, Nice, France

Hopital Saint Louis, Paris, France

Hopital Saint Antoine, Paris, France

Centre Hospitalier Universitaire de Bordeaux - Hopital Haut Leveque, Pessac, France

Hopital Lyon Sud, Pierre-Bénite, France

Centre Hospitalier Universitaire de Rennes, Rennes, France

Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France

Centre Hospitalier Universitaire de Nancy - Hopital de Brabois, Vandœuvre-lès-Nancy, France

Universitaetsklinikum Augsburg, Augsburg, Germany

Charite - Universitaetsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany

Universitaetsklinikum Dresden, Dresden, Germany

Universitaetsklinikum Duesseldorf, Düsseldorf, Germany

Universitaetsklinikum Heidelberg, Heidelberg, Germany

Universitaetsklinikum Jena, Jena, Germany

Universitaetsklinikum Schleswig-Holstein - Kiel, Kiel, Germany

Klinikum der LMU Muenchen, München, Germany

Evangelismos Hospital, Athens, Greece

Laiko General Hospital of Athens, Athens, Greece

Attiko General University Hospital, Athens, Greece

University Hospital of Heraklion, Heraklion, Greece

University Hospital of Ioannina, Ioannina, Greece

University Hospital of Larissa, Larissa, Greece

University Hospital of Patras, Pátrai, Greece

General Hospital of Thessaloniki Georgios Papanikolaou, Thessaloniki, Greece

Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong

Princess Margaret Hospital, Kowloon, Hong Kong

Tuen Mun Hospital, New Territories, Hong Kong

Semmelweis Egyetem, Budapest, Hungary

Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet, Budapest, Hungary

Debreceni Egyetem Klinikai Kozpont, Debrecen, Hungary

Heves Varmegyei Markhot Ferenc Oktatokorhaz es Rendelointezet, Eger, Hungary

Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz Nyiregyhazi Josa Andras Tagkorhaz, Nyíregyháza, Hungary

Rambam Medical Center, Haifa, Israel

Shaare Zedek Medical Center, Jerusalem, Israel

Rabin Medical Center - Beilinson Hospital, Petah Tikva, Israel

Azienda Ospedaliera Universitaria Consorziale Policlinico di Bari, Bari, Italy

Azienda Socio Sanitaria Territoriale Papa Giovanni xxiii, Bergamo, Italy

IRCCS Azienda Ospedaliero Universitaria di Bologna Policlinico di Sant Orsola, Bologna, Italy

Ospedale Policlinico San Martino IRCCS, Genova, Italy

Azienda Unita Sanitaria Locale LE Presidio Ospedaliero Vito Fazzi Polo Oncologico Giovanni Paolo II, Lecce, Italy

Azienda Unità Locale Socio Sanitaria 3 Ospedale Dell Angelo, Mestre (VE), Italy

Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy

Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli, Naples, Italy

Azienda Ospedaliera di Perugia Ospedale Santa Maria della Misericordia, Perugia, Italy

Azienda Unita Sanitaria Locale Pescara Ospedale Civile Santo Spirito, Pescara, Italy

Azienda Ospedaliera Policlinico Umberto I, Roma, Italy

Azienda Ospedaliero Universitaria Citta della Salute e della Scienza di Torino, Torino, Italy

Azienda Ospedaliera Universitaria Integrata di Verona Ospedale G B Rossi Borgo Roma, Verona, Italy

Nagoya University Hospital, Nagoya, Aichi-ken, Japan

Akita University Hospital, Akita, Akita, Japan

Tesshokai Kameda General Hospital, Kamogawa-shi, Chiba, Japan

University of Fukui Hospital, Yoshida-gun, Fukui, Japan

Kyushu University Hospital, Fukuoka, Fukuoka, Japan

Kurume University Hospital, Kurume-shi, Fukuoka, Japan

Fukushima Medical University Hospital, Fukushima, Fukushima, Japan

Gunma Saiseikai Maebashi Hospital, Maebashi, Gunma, Japan

Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan

Kobe City Medical Center General Hospital, Kobe, Hyōgo, Japan

Kanazawa University Hospital, Kanazawa, Ishikawa-ken, Japan

Tokai University Hospital, Isehara-shi, Kanagawa, Japan

Yokohama City University Medical Center, Yokohama, Kanagawa, Japan

Kyoto University Hospital, Kyoto, Kyoto, Japan

Tohoku University Hospital, Sendai, Miyagi, Japan

Nagasaki University Hospital, Nagasaki, Nagasaki, Japan

National Hospital Organization Okayama Medical Center, Okayama, Okayama-ken, Japan

Osaka Metropolitan University Hospital, Osaka, Osaka, Japan

Kindai University Hospital, Sakai-shi, Osaka, Japan

Jichi Medical University Hospital, Shimotsuke-shi, Tochigi, Japan

Tokyo Metropolitan Komagome Hospital, Bunkyo-ku, Tokyo, Japan

Nihon University Itabashi Hospital, Itabashi-ku, Tokyo, Japan

Yamagata University Hospital, Yamagata, Yamagata, Japan

Boca Clinical Trials Mexico SC, Mexico City, Mexico City, Mexico

Centro Oncologico Internacional, Mexico City, Mexico City, Mexico

Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Nuevo León, Mexico

Hematologica Alta Especialidad, Huixquilucan, Mexico

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico

Universitair Medisch Centrum Groningen, Groningen, Netherlands

Unidade Local de Saude de Coimbra, EPE, Coimbra, Portugal

Instituto Portugues de Oncologia de Lisboa Francisco Gentil, EPE, Lisbon, Portugal

Unidade Local de Saude de Sao Jose, EPE - Hospital de Santo Antonio dos Capuchos, Lisbon, Portugal

Unidade Local de Saude de Santa Maria, EPE - Hospital de Santa Maria, Lisbon, Portugal

Instituto Portugues de Oncologia do Porto Francisco Gentil, EPE, Porto, Portugal

Institutul Clinic Fundeni, Bucharest, Romania

Spitalul Universitar de Urgenta Bucuresti, Bucharest, Romania

Institutul Oncologic Prof Dr Ion Chiricuta, Cluj-Napoca, Romania

Spitalul Clinic Municipal Filantropia Craiova, Craiova, Romania

Institutul Regional de Oncologie Iasi, Iași, Romania

Spitalul Clinic Judetean de Urgenta Sibiu, Sibiu, Romania

Narodny onkologicky ustav, Bratislava, Slovakia

Univerzitna nemocnica Bratislava, Nemocnica sv Cyrila a Metoda, Bratislava, Slovakia

Dong-A University Hospital, Busan, South Korea

Pusan National University Hospital, Busan, South Korea

Chungnam National University Hospital, Daejeon, South Korea

Chonnam National University Hwasun Hospital, Hwasun, South Korea

Seoul National University Hospital, Seoul, South Korea

Severance Hospital Yonsei University Health System, Seoul, South Korea

The Catholic University of Korea Seoul St Marys Hospital, Seoul, South Korea

Hospital Universitario Reina Sofia, Córdoba, Andalusia, Spain

Hospital Universitario Virgen del Rocio, Seville, Andalusia, Spain

Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain

Complejo Asistencial Universitario de Salamanca Hospital Universitario de Salamanca, Salamanca, Castille and León, Spain

Institut Catala d Oncologia Badalona Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain

Hospital Universitari Vall d Hebron, Barcelona, Catalonia, Spain

Institut Catala d Oncologia Hospitalet Hospital Duran i Reynals, L'Hospitalet de Llobregat, Catalonia, Spain

Hospital Universitari i Politecnic La Fe, Valencia, Valencia, Spain

Hospital Universitario 12 de Octubre, Madrid, Spain

Sahlgrenska Universitetssjukhuset, Gothenburg, Sweden

Inselspital Bern, Bern, Switzerland

China Medical University Hospital, Taichung, Taiwan

Taichung Veterans General Hospital, Taichung, Taiwan

National Cheng Kung University Hospital, Tainan, Taiwan

National Taiwan University Hospital, Taipei, Taiwan

Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation, Taoyuan, Taiwan

Hacettepe Universitesi Tip Fakultesi Hastanesi, Ankara, Turkey (Türkiye)

Ankara Bilkent Sehir Hastanesi, Ankara, Turkey (Türkiye)

Memorial Antalya Hastanesi, Antalya, Turkey (Türkiye)

Bagcilar Medipol Mega Universite Hastanesi, Istanbul, Turkey (Türkiye)

Dokuz Eylul Universitesi Tip Fakultesi Hastanesi, Izmir, Turkey (Türkiye)

Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi, Samsun, Turkey (Türkiye)

University College London, London, United Kingdom

Kings College Hospital, London, United Kingdom