A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

Israel

Active Not RecruitingPHASE3

Simple summaryAI-assisted

This summary is produced by a language model and is experimental. It may be incomplete or inaccurate and is not a substitute for professional medical advice.

Conditions

Carcinoma, Non-Small-Cell Lung

Locations

Southern Cancer Center, PC, Mobile, Alabama, United States
Arizona Oncology Associates, Tucson, Arizona, United States
City of Hope, Duarte, California, United States
Cedars Sinai Medical Center, Los Angeles, California, United States
University of California Irvine, Orange, California, United States
Rocky Mountain Cancer Centers, Colorado Springs, Colorado, United States
Holy Cross Hospital - Michael and Dianne Bienes Comprehensive Cancer Center, Fort Lauderdale, Florida, United States
University Cancer And Blood Center LLC, Athens, Georgia, United States
University of Mississippi Medical Center, Jackson, Mississippi, United States
Nebraska Cancer Specialists, Grand Island, Nebraska, United States
Astera Cancer Care, East Brunswick, New Jersey, United States
TriHealth Network, Cincinnati, Ohio, United States
Providence Portland Medical Center, Portland, Oregon, United States
Kaiser Permanente Northwest, Portland, Oregon, United States
Alliance Cancer Specialists, Horsham, Pennsylvania, United States
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Baptist Cancer Center, Memphis, Tennessee, United States
Texas Oncology-Medical City Dallas, Dallas, Texas, United States
Texas Oncology Baylor Charles A Sammons Cancer Center, Dallas, Texas, United States
Texas Oncology, Grapevine, Texas, United States
Oncology Consultants Texas, Houston, Texas, United States
Texas Oncology - Northeast, Longview, Texas, United States
University of Vermont Medical Center, Burlington, Vermont, United States
University of Virginia, Charlottesville, Virginia, United States
Virginia Cancer Specialists, Fairfax, Virginia, United States
Blue Ridge Cancer Care, Wytheville, Virginia, United States
NorthWest Medical Specialties, PLLC, Puyallup, Washington, United States
Compass Oncology, Vancouver, Washington, United States
CINME Centro de Investigaciones Metabolicas, Caba, Argentina
IADT Instituto Argentino de Diagnostico y Tratamiento, CABA, Argentina
Centro Medico Fleischer, CABA, Argentina
CEMIC (Centro de Educación Médica e Investigaciones Clínicas), CABA, Argentina
Cemaic Centro Privado de Especialidades Medicas Ambulatorias e Investigacion Clinica, Córdoba, Argentina
Hospital Privado Universitario De Cordoba, Córdoba, Argentina
Hospital Privado de la Comunidad, Mar del Plata, Argentina
Clínica Viedma, Viedma, Argentina
Grand Hopital De Charleroi Site Les Viviers, Charleroi, Belgium
UZA, Edegem, Belgium
UZ Gent, Ghent, Belgium
Jessa Ziekenhuis - Campus Virga Jesse, Hasselt, Belgium
UZ Leuven, Leuven, Belgium
CHU Sart-Tilman, Liège, Belgium
Clinique Saint Pierre, Ottignies, Belgium
Cetus Oncologia, Belo Horizonte, Brazil
CIONC Centro Integrado de Oncologia de Curitiba, Curitiba, Brazil
Ynova Pesquisa Clinica, Florianópolis, Brazil
Fundacao Sao Francisco Xavier, Ipatinga, Brazil
UPCO Unidade de Pesquisa Clinica em Oncologia, Pelotas, Brazil
Associacao Hospitalar Moinhos de Vento, Porto Alegre, Brazil
Hospital Ernesto Dornelles, Porto Alegre, Brazil
Oncoclinicas Rio de Janeiro S A, Rio de Janeiro, Brazil
Instituto D Or de Pesquisa e Ensino IDOR, Rio de Janeiro, Brazil
Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI), Rio de Janeiro, Brazil
Nucleo de Oncologia da Bahia, Salvador, Brazil
Hospital Sao Rafael, Salvador, Brazil
CEPHO Centro de Estudos e Pesquisa de Hematologia e Oncologia, Santo André, Brazil
Real e Benemerita Associacao Portuguesa de Beneficencia, São Paulo, Brazil
Hospital Paulistano, São Paulo, Brazil
Hospital Alemao Oswaldo Cruz, São Paulo, Brazil
Hospital Nove de Julho, São Paulo, Brazil
Fundacao Antonio Prudente A C Camargo Cancer Center, São Paulo, Brazil
Onco Star SP Oncologia Ltda, São Paulo, Brazil
IOS - Instituto de Oncologia de Sorocaba Dr. Gilson Delgado, Sorocaba, Brazil
COT - Centro Oncologico do Triangulo S.A, Uberlândia, Brazil
Multifunctional Hospital for Active Treatment 'Serdika', Sofia, Bulgaria
Multiprofile Hospital for Active Treatment 'Tokuda Hospital Sofia', Sofia, Bulgaria
Specialized Hospital for Active Treatment in Oncology, Sofia, Bulgaria
UMHAT Sofia Med, Sofia, Bulgaria
Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta, Canada
British Columbia Cancer Agency, Vancouver, British Columbia, Canada
McGill University Health Centre, Montreal, Quebec, Canada
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China
Peking University People's Hospital, Beijing, China
Beijing Cancer Hospital Chest Tumor Internal Medicine dept. II, Beijing, China
Beijing Cancer Hospital, Beijing, China
Chinese PLA General Hospital, Beijing, China
Beijing Chest hospital, Capital medical university, Beijing, China
Hunan Cancer Hospital Chest Tumor Internal Medicine dept. II, Changsha, China
Hunan Cancer hospital, Changsha, China
Sichuan Cancer Hospital, Chengdu, China
West China Hospital Sichuan University, Chengdu, China
Chongqing University Cancer Hospital, Chongqing, China
Southwest Hospital, Chongqing, China
Daping Hospital Army Characteristic Medical Center, Chongqing, China
The First Affiliated Hospital Sun Yat sen University, Guangzhou, China
Sun Yat-Sen Memorial Hospital Sun Yat-sen University, Guangzhou, China
Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
The Second Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou, China
Sir Run Run Shaw Hospital Zhejiang University School of Medicine, Hangzhou, China
Zhejiang Cancer Hospital, Hangzhou, China
Harbin medical university cancer hospital, Harbin, China
Huizhou Municipal Central Hospital, Huizhou, China
Taizhou Hospital of Zhejiang Province, Linhai, China
Affiliated Hospital of North Sichuan Medical College, Nanchong, China
Ruijin Hospital Shanghai Jiao Tong University, Shanghai, China
Fudan University Shanghai Cancer Center, Shanghai, China
Shanghai East Hospital, Shanghai, China
Shenzhen university General Hospital, Shenzhen, China
Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen, China
Tianjin Medical University General Hospital, Tianjin, China
Weifang People's Hospital, Weifang, China
The First Affiliated Hospital of Xian Jiaotong University, Xi'an, China
Yantai Yuhuangding Hospital, Yantai, China
Henan Cancer Hospital, Zhengzhou, China
Fakultni nemocnice Olomouc - I.P.Pavlova 6, Olomouc, Czechia
Vitkovicka nemocnice a.s., Ostrava- Vitkovice, Czechia
Fakultni nemocnice Plzen, Pilsen, Czechia
Rigshospitalet, Copenhagen, Denmark
Institut Sainte Catherine, Avignon, France
Hospices Civils de Lyon HCL, Bron, France
CHU de Grenoble Hopital Albert Michallon, La Tronche, France
Centre Hospitalier du Mans, Le Mans, France
CHR Hôpital Calmette, Lille, France
Hopital Nord, Marseille, France
CHU de Montpellier - Arnaud de Villeneuve, Montpellier, France
Institut Curie, Paris, France
CHU Bordeaux, Pessac, France
CHRU Hopital de Pontchaillou, Rennes, France
CHU Nantes, Sain-Herblain, France
Nouvel Hopital Civil - CHU Strasbourg, Strasbourg, France
CHU Bretonneau, Tours, France
Evangelische Lungenklinik Berlin, Berlin, Germany
Asklepios Klinikum Harburg, Hamburg, Germany
Thoraxklinik am Universitatsklinikum Heidelberg, Heidelberg, Germany
Onkologische Schwerpunktpraxis, Heilbronn, Germany
POIS Sachsen GmbH iG, Leipzig, Germany
Bethanien Krankenhaus, Moers, Germany
Klinikum der Universitaet Muenchen, München, Germany
Oncologianova GmbH, Recklinghausen, Germany
Universitaetsklinikum Regensburg, Regensburg, Germany
Queen Mary Hospital, Hong Kong, Hong Kong
Health Care Global Enterprises pvt Ltd, Bangalore, India
Artemis Hospital, Gurugram, India
Tata Medical Center, Kolkata, India
Tata Memorial Hospital, Mumbai, India
HCG Manavta Cancer Centre, Nashik, India
Rajiv Gandhi Cancer Institute and Research Centre, New Delh, India
Noble Hospital Pvt Ltd, Pune, India
Bhaktivedanta Hospital & Research Institute, Thane, India
Soroka University Medical Center, Beersheba, Israel
Rambam Health Corporation, Haifa, Israel
Shaare Zedek Medical Center, Jerusalem, Israel
Meir Medical Center, Kfar Saba, Israel
Rabin Medical Center, Petah Tikva, Israel
Chaim Sheba Medical Center, Ramat Gan, Israel
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
CRO IRCCS Istituto Nazionale Tumori, Aviano, Italy
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy
Istituto Europeo di Oncologia, Milan, Italy
Azienda Ospedaliero-Universitaria Di Parma, Parma, Italy
Ospedale S. Maria Delle Croci, Ravenna, Italy
Istituto Nazionale Tumori Regina Elena, Roma, Italy
Policlinico G.B.Rossi, Verona, Italy
National Hospital Organization Shibukawa Medical Center, Gunma, Japan
Hyogo Cancer Center, Hyōgo, Japan
Kanagawa Cancer Center, Kanagawa, Japan
Kobe City Medical Center General Hospital, Kobe, Japan
Kurume University Hospital, Kurume, Japan
National Hospital Organization Nagoya Medical Center, Nagoya, Japan
Niigata Cancer Center Hospital, Niigata, Japan
Osaka International Cancer Institute, Osaka, Japan
Shizuoka Cancer Center, Shizuoka, Japan
Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan
The Cancer Institute Hospital of JFCR, Tokyo, Japan
Ehime University Hospital, Toon-shi, Japan
Wakayama Medical University Hospital, Wakayama, Japan
National Hospital Organization Iwakuni Clinical Center, Yamaguchi, Japan
National Hospital Organization Yamaguchi Ube Medical Center, Yamaguchi, Japan
University Malaya Medical Centre, Kuala Lumpur, Malaysia
Hospital Tengku Ampuan Afzan, Kuantan, Malaysia
Beacon Hospital Sdn Bhd, Petaling Jaya, Malaysia
Subang Jaya Medical Centre, Subang Jaya, Malaysia
Mount Miriam Cancer Hospital, Tanjung Bungah, Malaysia
Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Mexico
CIMOVA, Morals Vargas Centro de Investigación SC, León, Mexico
Health Pharma Professional Research, México, Mexico
Instituto Nacional de Cancerologia, México, Mexico
Oncologia Integral Satelite, Naucalpan, Mexico
VUMC Amsterdam, Amsterdam, Netherlands
Ziekenhuis St Jansdal, Harderwijk, Netherlands
Erasmus MC, Rotterdam, Netherlands
Centrum Onkologii im Prof F Lukaszczyka, Bydgoszcz, Poland
Uniwersyteckie Centrum Kliniczne, Gdansk, Poland
Szpitale Pomorskie Sp z o o, Gdynia, Poland
Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie, Olsztyn, Poland
Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeylandow, Poznan, Poland
Private Specialist Hospitals - MedPolonia, Poznan, Poland
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy, Warsaw, Poland
Uls Santa Maria - Hosp. Pulido Valente, Lisbon, Portugal
Uls Loures Odivelas - Hosp. Loures, Loures, Portugal
Uls Santo Antonio - Hosp. Santo Antonio, Porto, Portugal
Instituto Portugues de Oncologia, Porto, Portugal
Pan American Center for Oncology Trials LLC, Rio Piedras, Puerto Rico
City Clinical Hospital #1, Nal'chik, Russia
Llc, Eurocityclinic, Saint Petersburg, Russia
National Cancer Center, Gyeonggi-do, South Korea
CHA Bundang Medical Center, CHA University, Gyeonggi-do, South Korea
Seoul National University Bundang Hospital, Gyeonggi-do, South Korea
GyeongSang National University Hospital, Gyeongsangnam-do, South Korea
Korea University Anam Hospital, Seoul, South Korea
Severance Hospital Yonsei University Health System, Seoul, South Korea
Asan Medical Center, Seoul, South Korea
Samsung Medical Center, Seoul, South Korea
The Catholic University of Korea Seoul St Mary s Hospital, Seoul, South Korea
Hosp Univ A Coruna, A Coruña, Spain
Hosp. de La Santa Creu I Sant Pau, Barcelona, Spain
Hosp. Univ. Quiron Dexeus, Barcelona, Spain
Hosp Univ Vall D Hebron, Barcelona, Spain
Hosp Clinic de Barcelona, Barcelona, Spain
Hosp. Univ. Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain
Hosp. Gral. Univ. Gregorio Maranon, Madrid, Spain
Hosp Univ Fund Jimenez Diaz, Madrid, Spain
Hosp. Univ. 12 de Octubre, Madrid, Spain
Hosp. Univ. La Paz, Madrid, Spain
Hosp Univ Hm Sanchinarro, Madrid, Spain
Hosp. Univ. Pta. de Hierro Majadahonda, Majadahonda, Spain
Hosp Regional Univ de Malaga, Málaga, Spain
Clinica Univ. de Navarra, Pamplona, Spain
Hosp. Virgen Del Rocio, Seville, Spain
Hosp. Gral. Univ. Valencia, Valencia, Spain
Hosp. Univ. I Politecni La Fe, Valencia, Spain
Sahlgrenska Universitetssjukhuset, Gothenburg, Sweden
Linkoping University Hospital, Linköping, Sweden
Skanes universitetssjukhus, Lund, Sweden
Norrlands Universitetssjukhus, Umeå, Sweden
Akademiska Sjukhuset, Uppsala, Sweden
Changhua Christian Hospital, Changhua, Taiwan
Kaohsiung Medical University Chung Ho Memorial Hospital, Kaohsiung City, Taiwan
Taipei Medical University Shuang Ho Hospital, New Taipei City, Taiwan
Chung Shan Medical University Hospital, Taichung, Taiwan
Taichung Veterans General Hospital, Taichung, Taiwan
National Cheng Kung University Hospital, Tainan, Taiwan
National Taiwan University Hospital, Taipei, Taiwan
Adana City Hospital, Adana, Turkey (Türkiye)
Memorial Ankara Hastanesi, Ankara, Turkey (Türkiye)
Gazi University Hospital, Ankara, Turkey (Türkiye)
Ankara Bilkent City Hospital, Ankara, Turkey (Türkiye)
Trakya University Medical Faculty, Edirne, Turkey (Türkiye)
Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey (Türkiye)
Bakirkoy Training and Research Hospital, Istanbul, Turkey (Türkiye)
Medipol Mega University Hospital, Istanbul, Turkey (Türkiye)
Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi, Istanbul, Turkey (Türkiye)
Medical Point, Izmir, Turkey (Türkiye)
Velindre Hospital, Cardiff, United Kingdom
Edinburgh Cancer Centre Western General, Edinburgh, United Kingdom
UCL Cancer Institute, London, United Kingdom
Guys and St Thomas NHS Foundation Trust, London, United Kingdom
The Royal Marsden NHS Trust, London, United Kingdom
The Christie Nhs Foundation Trust, Manchester, United Kingdom

View source on ClinicalTrials.gov